Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50015504
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156754((S)-N-methoxy-4-methyl-3-(4-(methyl(neopentyl)amin...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156743((S)-N-hydroxy-4-methyl-3-(4-(methyl(neopentyl)amin...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156750(CHEMBL376506 | DEL-A, 5 | N-methoxy-4-methyl-3-(4-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human p38betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156757((S)-4-methyl-3-(4-(methyl(neopentyl)amino)-6-(pyrr...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156741((S)-3-(4-(isobutyl(methyl)amino)-6-(pyrrolidin-3-y...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156755((S)-N-ethyl-4-methyl-3-(4-(methyl(neopentyl)amino)...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156737((S)-N-isopropyl-4-methyl-3-(4-(methyl(neopentyl)-a...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156738(3-(4-(1,4-diazepan-1-yl)-6-(methyl(neopentyl)amino...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156752(3-(4-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]heptan...)
Affinity DataIC50: 53nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156742(N-methoxy-4-methyl-3-(4-(methyl(neopentyl)amino)-6...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156756((S)-N-benzyl-4-methyl-3-(4-(methyl(neopentyl)amino...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156747((S)-3-(4-(isobutylamino)-6-(pyrrolidin-3-ylamino)-...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156739(4-methyl-3-(4-(methyl(2-phenylpropyl)amino)-6-((S)...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156746((S)-N-cyclopentyl-4-methyl-3-(4-(methyl(neopentyl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156749((S)-3-(4-(4-fluorophenethylamino)-6-(pyrrolidin-3-...)
Affinity DataIC50: 227nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156744((S)-3-(4-(cyclohexyl(methyl)amino)-6-(pyrrolidin-3...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156748((S)-N-(2-methoxyethyl)-4-methyl-3-(4-(methyl(neope...)
Affinity DataIC50: 264nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156745((S)-methyl-4-methyl-3-(4-(methyl(neopentyl)amino)-...)
Affinity DataIC50: 346nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156753(4-methyl-3-(4-(methyl(neopentyl)amino)-6-(4-methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156736(3-(4-(1,4-diazepan-1-yl)-6-(((1S,2R,5S)-6,6-dimeth...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156751(3-(4-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]heptan...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156740(3-(4-amino-6-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1....)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human IKK2betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(CHEMBL225088 | 3-({4-[(2,2-dimethylpropyl)(methyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Zap70More data for this Ligand-Target Pair
In DepthDetails Article
PubMed