Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50015466
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156328(2,6-Dimethyl-4-[3-(3-{2-[1-(2-nitro-phenyl)-piperi...)
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156313(4-[3-(3-{2-[1-(2-Methoxy-phenyl)-piperidin-4-ylami...)
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156319(2,6-Dimethyl-4-(3-{3-[2-(1-phenyl-piperidin-4-ylam...)
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156317(N-arylpiperazine derivative | CHEMBL187925)
Affinity DataIC50: 3nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156326(4-[3-(3-{2-[1-(2-Cyano-phenyl)-piperidin-4-ylamino...)
Affinity DataIC50: 3nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156323(N-arylpiperazine derivative | CHEMBL189412)
Affinity DataIC50: 3nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156331(2,6-Dimethyl-4-(3-{3-[2-(1-o-tolyl-piperidin-4-yla...)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156311(N-arylpiperazine derivative | CHEMBL187620)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156316(N-arylpiperazine derivative | CHEMBL188576)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156318(N-arylpiperazine derivative | CHEMBL361273)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156314(N-arylpiperazine derivative | CHEMBL364380)
Affinity DataIC50: 5nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156322(2,6-Dimethyl-4-[3-(3-{2-[1-(2-methylsulfanyl-pheny...)
Affinity DataIC50: 5nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156312(4-[3-(3-{2-[1-(2-Hydroxy-phenyl)-piperidin-4-ylami...)
Affinity DataIC50: 6nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156321(N-arylpiperazine derivative | CHEMBL187490)
Affinity DataIC50: 8nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156315(4-[3-(3-{2-[1-(3-Chloro-phenyl)-piperidin-4-ylamin...)
Affinity DataIC50: 8nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156325(N-arylpiperazine derivative | CHEMBL188790)
Affinity DataIC50: 10nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109185(BMS-189323 | 4-[3-(3-{3-[4-(2-Methoxy-phenyl)-pipe...)
Affinity DataIC50: 12nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156327(N-arylpiperazine derivative | CHEMBL189036)
Affinity DataIC50: 14nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156324(2,6-Dimethyl-4-[3-(3-{2-[1-(2-trifluoromethoxy-phe...)
Affinity DataIC50: 25nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156329(N-arylpiperazine derivative | CHEMBL187782)
Affinity DataIC50: 28nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156320(2,6-Dimethyl-4-[3-(3-{2-[1-(2-trifluoromethyl-phen...)
Affinity DataIC50: 31nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156330(BMS-245782 | N-arylpiperazine derivative | CHEMBL1...)
Affinity DataIC50: 39nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156313(4-[3-(3-{2-[1-(2-Methoxy-phenyl)-piperidin-4-ylami...)
Affinity DataKi:  1.90nMAssay Description:Antagonist activity towards Neuropeptide Y receptor type 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156311(N-arylpiperazine derivative | CHEMBL187620)
Affinity DataKi:  3.60nMAssay Description:Antagonist activity towards Neuropeptide Y receptor type 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed