Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 4255
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataKi:  3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM50130950(CHEMBL310759 | 5-[(4-chlorophenyl)sulfanyl]quinazo...)
Affinity DataKi:  38nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM18046(CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...)
Affinity DataKi:  150nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM59168(5-(4-fluorophenoxy)quinazoline-2,4-diamine, 2b)
Affinity DataKi:  180nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM50130956(CHEMBL82334 | 5-(4-methylphenoxy)quinazoline-2,4-d...)
Affinity DataKi:  230nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM59166(6,7-dimethyl-5,6,7,8-tetrahydroquinazoline-2,4-dia...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM59167(6-methyl-5,6,7,8-tetrahydroquinazoline-2,4-diamine...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)