Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50037323
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150333(N-[3-(Benzyl-{4-[4-((1R,3S)-4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150336((4R,6S)-4-Hydroxy-6-({[4-((8S,11R,13S,14S,17S)-17-...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150336((4R,6S)-4-Hydroxy-6-({[4-((8S,11R,13S,14S,17S)-17-...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150332((S)-3,5-Dihydroxy-6-[4-((8S,11R,13S,14S,17S)-17-hy...)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50: 18nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150338(N-{3-[(2,4-Difluoro-benzyl)-(4-phenoxy-benzyl)-ami...)
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150336((4R,6S)-4-Hydroxy-6-({[4-((8S,11R,13S,14S,17S)-17-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150334(N-[3-((2,4-Difluoro-benzyl)-{4-[3-((2S,4R)-4-hydro...)
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150339((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...)
Affinity DataIC50: 37nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150332((S)-3,5-Dihydroxy-6-[4-((8S,11R,13S,14S,17S)-17-hy...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150339((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...)
Affinity DataIC50: 76nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50: 130nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150336((4R,6S)-4-Hydroxy-6-({[4-((8S,11R,13S,14S,17S)-17-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150339((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150339((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...)
Affinity DataIC50: 220nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 240nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 270nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50: 300nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150338(N-{3-[(2,4-Difluoro-benzyl)-(4-phenoxy-benzyl)-ami...)
Affinity DataIC50: 385nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150333(N-[3-(Benzyl-{4-[4-((1R,3S)-4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50: 440nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150332((S)-3,5-Dihydroxy-6-[4-((8S,11R,13S,14S,17S)-17-hy...)
Affinity DataIC50: 560nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150334(N-[3-((2,4-Difluoro-benzyl)-{4-[3-((2S,4R)-4-hydro...)
Affinity DataIC50: 670nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50: 760nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150332((S)-3,5-Dihydroxy-6-[4-((8S,11R,13S,14S,17S)-17-hy...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150338(N-{3-[(2,4-Difluoro-benzyl)-(4-phenoxy-benzyl)-ami...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150334(N-[3-((2,4-Difluoro-benzyl)-{4-[3-((2S,4R)-4-hydro...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150333(N-[3-(Benzyl-{4-[4-((1R,3S)-4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed