Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50014422
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142519(N-[2-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,...)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142517(N-[4-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,...)
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142507(N-[3-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,...)
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142519(N-[2-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,...)
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142517(N-[4-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142507(N-[3-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142526(N-[4-(3,4-dihydroxy-benzoylamino)-phenyl]-3,4-dihy...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142529(Acetic acid 2,3-diacetoxy-5-[2-(3,4,5-triacetoxy-b...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142509(N-[2-(3,4-dihydroxy-benzoylamino)-phenyl]-3,4-dihy...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142528(N-Benzothiazol-2-yl-3,4,5-trihydroxy-benzamide | C...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142514(Acetic acid 2,3-diacetoxy-5-[4-(3,4,5-triacetoxy-b...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142523(N-[3-(3,4-dihydroxy-benzoylamino)-phenyl]-3,4-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142510(Acetic acid 2,3-diacetoxy-5-[3-(3,4,5-triacetoxy-b...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142515(N-Benzothiazol-2-yl-3,4-dihydroxy-benzamide | CHEM...)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142525(N-(4,5-Dihydro-thiazol-2-yl)-3,4,5-trihydroxy-benz...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142513(Acetic acid 2-acetoxy-5-[3-(3,4-diacetoxy-benzoyla...)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142522(Acetic acid 2-acetoxy-5-[2-(3,4-diacetoxy-benzoyla...)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142530(3,4,5-Trihydroxy-N-phenyl-benzamide | CHEMBL43782)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142508(N-(2-Benzoylamino-phenyl)-benzamide | CHEMBL44839)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142527(N-Benzothiazol-2-yl-4-hydroxy-benzamide | CHEMBL29...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142524(Acetic acid 4-[2-(4-acetoxy-benzoylamino)-phenylca...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142521(N-(3-Benzoylamino-4-hydroxyphenyl)-4-hydroxy-benza...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142520(N-(4-Benzoylamino-4-hydroxyphenyl)-4-hydroxy-benza...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142518(Acetic acid 2-acetoxy-5-[4-(3,4-diacetoxy-benzoyla...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142516(Acetic acid 4-[3-(4-acetoxy-benzoylamino)-phenylca...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142512(N-(2-Benzoylamino-4-hydroxyphenyl)-4-hydroxy-benza...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142511(Acetic acid 4-[4-(4-acetoxy-benzoylamino)-phenylca...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142519(N-[2-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,...)
Affinity DataKi:  400nMAssay Description:Inhibition of relaxation activities of DNA topoisomerase I with respect to pBR322 DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142519(N-[2-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,...)
Affinity DataKi:  7.41E+4nMAssay Description:Inhibition of relaxation activities of DNA topoisomerase II with respect to pBR322 DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed