Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 1952
LigandPNGBDBM15459(4-{1-methyl-2-piperidin-4-yl-4-[3-(trifluoromethyl...)
Affinity DataIC50: 2nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15448(1,3-diethyl-5-[3-(3-methylphenyl)-1H-pyrazol-4-yl]...)
Affinity DataIC50: 9nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15442(1,3-diethyl-5-[3-(4-fluoro-3-methylphenyl)-1H-pyra...)
Affinity DataIC50: 30nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 38nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15458(SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...)
Affinity DataIC50: 40nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15419(1,3-diethyl-5-[4-(3-methylphenyl)-1H-imidazol-5-yl...)
Affinity DataIC50: 50nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15457(2-(4-fluorophenyl)-4-methoxy-3-(pyridin-4-yl)-1H-p...)
Affinity DataIC50: 52nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15443(1,3-diethyl-5-{3-[3-(trifluoromethyl)phenyl]-1H-py...)
Affinity DataIC50: 60nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15438(1,3-diethyl-5-[4-(3-methylphenyl)-2-(pyridin-3-yl)...)
Affinity DataIC50: 70nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15439(1,3-diethyl-5-[4-(3-methylphenyl)-2-(piperidin-4-y...)
Affinity DataIC50: 70nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15461(1,3-diethyl-5-[4-(4-fluorophenyl)-1-(piperidin-4-y...)
Affinity DataIC50: 90nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15421(1,3-diethyl-5-[4-(4-fluorophenyl)-1H-imidazol-5-yl...)
Affinity DataIC50: 100nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15418(1,3-dimethyl-5-[4-(3-methylphenyl)-1H-imidazol-5-y...)
Affinity DataIC50: 100nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15432(1,3-dimethyl-5-[4-(3-methylphenyl)-2-(thiophen-2-y...)
Affinity DataIC50: 140nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15420(5-[4-(4-fluorophenyl)-1H-imidazol-5-yl]-1,3-dimeth...)
Affinity DataIC50: 140nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15417(1,3-diethyl-5-(4-phenyl-1H-imidazol-5-yl)-2,3-dihy...)
Affinity DataIC50: 140nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15446(1,3-diethyl-5-(3-phenyl-1H-pyrazol-4-yl)-2,3-dihyd...)
Affinity DataIC50: 200nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15444(1,3-dimethyl-5-(3-phenyl-1H-pyrazol-4-yl)-2,3-dihy...)
Affinity DataIC50: 200nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15437(1,3-dimethyl-5-[4-(3-methylphenyl)-2-(pyridin-3-yl...)
Affinity DataIC50: 200nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15460(5-[6-amino-2-(3-methylphenyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50: 260nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15422(1,3-dimethyl-5-[4-phenyl-2-(thiophen-2-yl)-1H-imid...)
Affinity DataIC50: 260nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15425(5-[4-(4-fluorophenyl)-2-(thiophen-2-yl)-1H-imidazo...)
Affinity DataIC50: 270nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15416(1,3-dimethyl-5-(4-phenyl-1H-imidazol-5-yl)-2,3-dih...)
Affinity DataIC50: 290nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15423(5-[4-(2-fluorophenyl)-2-(thiophen-2-yl)-1H-imidazo...)
Affinity DataIC50: 370nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15427(5-[4-(3-chlorophenyl)-2-(thiophen-2-yl)-1H-imidazo...)
Affinity DataIC50: 380nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15424(5-[4-(3-fluorophenyl)-2-(thiophen-2-yl)-1H-imidazo...)
Affinity DataIC50: 390nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15434(5-[4-(3-ethylphenyl)-2-(thiophen-2-yl)-1H-imidazol...)
Affinity DataIC50: 500nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15426(5-[4-(2-chlorophenyl)-2-(thiophen-2-yl)-1H-imidazo...)
Affinity DataIC50: 540nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15428(5-[4-(4-chlorophenyl)-2-(thiophen-2-yl)-1H-imidazo...)
Affinity DataIC50: 680nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15447(1,3-diethyl-5-(4-phenyl-1H-pyrazol-3-yl)-2,3-dihyd...)
Affinity DataIC50: 680nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15455(1,3-diethyl-5-[1-(3-methylphenyl)-1H-pyrazol-5-yl]...)
Affinity DataIC50: 690nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15449(1,3-diethyl-5-[4-(3-methylphenyl)-1H-pyrazol-3-yl]...)
Affinity DataIC50: 730nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15451(1,3-diethyl-5-[4-(3-methylphenyl)-1,3-oxazol-5-yl]...)
Affinity DataIC50: 800nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15415(1,3-diethyl-5-(1H-imidazol-5-yl)-2,3-dihydro-1H-1,...)
Affinity DataIC50: 1.00E+3nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15441(1,3-diethyl-5-[2-(3-methylphenyl)-5-(pyridin-3-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15456(1,3-diethyl-5-[2-(3-methylphenyl)pyridin-3-yl]-2,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15452(1,3-diethyl-5-[5-(4-fluoro-3-methylphenyl)-1H-1,2,...)
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15453(1,3-diethyl-5-[1-(4-fluoro-3-methylphenyl)-1H-1,2,...)
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15462(1,3-diethyl-5-[1-methyl-4-(3-methylphenyl)-2-(pipe...)
Affinity DataIC50: 1.25E+3nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15430(1,3-dimethyl-5-[2-(thiophen-2-yl)-4-[3-(trifluorom...)
Affinity DataIC50: 1.50E+3nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15433(1,3-dimethyl-5-[4-(4-methylphenyl)-2-(thiophen-2-y...)
Affinity DataIC50: 1.80E+3nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15445(1,3-dimethyl-5-(4-phenyl-1H-pyrazol-3-yl)-2,3-dihy...)
Affinity DataIC50: 2.50E+3nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15440(5-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50: 4.00E+3nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15431(1,3-dimethyl-5-[4-(2-methylphenyl)-2-(thiophen-2-y...)
Affinity DataIC50: 6.20E+3nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15435(5-[4-(4-ethylphenyl)-2-(thiophen-2-yl)-1H-imidazol...)
Affinity DataIC50: 8.00E+3nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15450(1,3-dimethyl-5-[3-(3-methylphenyl)-4H-1,2,4-triazo...)
Affinity DataIC50: 1.25E+4nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15454(1,3-dimethyl-5-[1-(3-methylphenyl)-1H-imidazol-5-y...)
Affinity DataIC50: 1.44E+4nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15429(1,3-dimethyl-5-[2-(thiophen-2-yl)-4-[3-(trifluorom...)
Affinity DataIC50: 1.58E+4nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
LigandPNGBDBM15436(1,3-dimethyl-5-{4-[3-(propan-2-yl)phenyl]-2-(thiop...)
Affinity DataIC50: 3.20E+4nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed