Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 1213
LigandPNGBDBM10112((3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methyli...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10109((3Z)-4-[(3R,4S,5R)-4-amino-3,5-dihydroxyhex-1-yn-1...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10099((3Z)-4-[(3S)-3-amino-4-hydroxybut-1-yn-1-yl]-5-flu...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10095((3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methyli...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10110((3Z)-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-3-...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10098((3Z)-4-(4-amino-3-hydroxybut-1-yn-1-yl)-5-fluoro-3...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10100((3Z)-5-fluoro-4-[(3S)-4-hydroxy-3-(methylamino)but...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10113((3Z)-5-fluoro-4-{2-[(2S,4R)-4-hydroxypyrrolidin-2-...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10114((3Z)-5-fluoro-4-{2-[(2S,4S)-4-hydroxypyrrolidin-2-...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10101((3Z)-4-[(3R)-3-amino-4-hydroxybut-1-yn-1-yl]-5-flu...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10111((3Z)-5-fluoro-4-[2-(4-hydroxypiperidin-4-yl)ethyny...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10106((3Z)-5-fluoro-4-[(3R,4R)-4-hydroxy-3-(methylamino)...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10102((3Z)-5-fluoro-4-[(3R)-4-hydroxy-3-(methylamino)but...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10105((3Z)-4-[(3R,4R)-3-amino-4-hydroxypent-1-yn-1-yl]-5...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10107((3Z)-4-[(3R,4R)-3-(ethylamino)-4-hydroxypent-1-yn-...)
Affinity DataIC50: 18nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10103((3Z)-4-[(3R)-3-(ethylamino)-4-hydroxybut-1-yn-1-yl...)
Affinity DataIC50: 21nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10096((3Z)-5-fluoro-4-[(3R)-3-hydroxybut-1-yn-1-yl]-3-[(...)
Affinity DataIC50: 21nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10097((3Z)-5-fluoro-4-[(3S)-3-hydroxybut-1-yn-1-yl]-3-[(...)
Affinity DataIC50: 26nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10108(N-[(3R,4R)-1-[(3Z)-5-fluoro-3-[(3-methoxy-1H-pyrro...)
Affinity DataIC50: 45nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10104((3Z)-5-fluoro-4-[(3R)-4-hydroxy-3-[(2-hydroxyethyl...)
Affinity DataIC50: 95nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10074((3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methyli...)
Affinity DataIC50: 847nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed
LigandPNGBDBM10094((3Z)-5-fluoro-4-iodo-3-[(3-methoxy-1H-pyrrol-2-yl)...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed