Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50014358
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141447(N-[6-Cyclopentylamino-9-((2R,3R,4S,5R)-3,4-dihydro...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141452(3-Cyclopentyl-N-[6-cyclopentylamino-9-((2R,3R,4S,5...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141455(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141453(2-Cyclohexyl-N-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-h...)
Affinity DataKi:  181nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141453(2-Cyclohexyl-N-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-h...)
Affinity DataKi:  207nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141451(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  252nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141449(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  342nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141456(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  432nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141450(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  733nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141455(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141448((2S,3S,4R,5R)-5-[6-Amino-2-(3-cyclopentyl-propiony...)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141451(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141450(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141449(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  1.23E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141447(N-[6-Cyclopentylamino-9-((2R,3R,4S,5R)-3,4-dihydro...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141452(3-Cyclopentyl-N-[6-cyclopentylamino-9-((2R,3R,4S,5...)
Affinity DataKi:  1.41E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141454(Cyclohexanecarboxylic acid [6-amino-9-((2R,3R,4S,5...)
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141454(Cyclohexanecarboxylic acid [6-amino-9-((2R,3R,4S,5...)
Affinity DataKi:  1.78E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141450(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  1.94E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141451(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141452(3-Cyclopentyl-N-[6-cyclopentylamino-9-((2R,3R,4S,5...)
Affinity DataKi:  2.18E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  2.27E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141449(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  2.41E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141456(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  2.71E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141454(Cyclohexanecarboxylic acid [6-amino-9-((2R,3R,4S,5...)
Affinity DataKi:  2.76E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141455(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141456(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  4.57E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141448((2S,3S,4R,5R)-5-[6-Amino-2-(3-cyclopentyl-propiony...)
Affinity DataKi:  5.45E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141447(N-[6-Cyclopentylamino-9-((2R,3R,4S,5R)-3,4-dihydro...)
Affinity DataKi:  5.66E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141453(2-Cyclohexyl-N-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-h...)
Affinity DataKi:  7.75E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141448((2S,3S,4R,5R)-5-[6-Amino-2-(3-cyclopentyl-propiony...)
Affinity DataKi:  1.08E+4nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed