Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50037287
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140110((R)-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyph...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140098(1-(2,6-Difluoro-benzyl)-5-(2-fluoro-3-methoxy-phen...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140103((S)-1-(2,6-difluorobenzyl)-3-(2-(cyclopentylamino)...)
Affinity DataIC50: 5.5nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140111((R)-1-(2,6-difluorobenzyl)-3-(1-(2-methoxybenzylam...)
Affinity DataIC50: 5.70nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140097(1-(2,6-Difluoro-benzyl)-5-(2-fluoro-3-methoxy-phen...)
Affinity DataIC50: 6.10nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140101(3-[2-((S)-Cyclobutylamino)-propyl]-1-(2,6-difluoro...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140109(1-(2,6-Difluoro-benzyl)-3-[(S)-2-(1-ethyl-propylam...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132728(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140095(1-(2,6-Difluoro-benzyl)-3-{(S)-2-[(5-ethyl-furan-2...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140102(3-((S)-2-Benzylamino-propyl)-1-(2,6-difluoro-benzy...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of [Ca2+] influx in RBL cells expressing Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140110((R)-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyph...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140096(1-(2,6-Difluoro-benzyl)-5-(2-fluoro-3-methoxy-phen...)
Affinity DataKi:  3nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140111((R)-1-(2,6-difluorobenzyl)-3-(1-(2-methoxybenzylam...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140098(1-(2,6-Difluoro-benzyl)-5-(2-fluoro-3-methoxy-phen...)
Affinity DataKi:  4nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140109(1-(2,6-Difluoro-benzyl)-3-[(S)-2-(1-ethyl-propylam...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140103((S)-1-(2,6-difluorobenzyl)-3-(2-(cyclopentylamino)...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140101(3-[2-((S)-Cyclobutylamino)-propyl]-1-(2,6-difluoro...)
Affinity DataKi:  5nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140115(1-(2,6-Difluoro-benzyl)-5-(2-fluoro-3-methoxy-phen...)
Affinity DataKi:  7nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140097(1-(2,6-Difluoro-benzyl)-5-(2-fluoro-3-methoxy-phen...)
Affinity DataKi:  13nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140095(1-(2,6-Difluoro-benzyl)-3-{(S)-2-[(5-ethyl-furan-2...)
Affinity DataKi:  15nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140095(1-(2,6-Difluoro-benzyl)-3-{(S)-2-[(5-ethyl-furan-2...)
Affinity DataKi:  15nMAssay Description:In vivo inhibition of monkey Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132729((R)-1-(2,6-difluorobenzyl)-5-(3-methoxyphenyl)-6-m...)
Affinity DataKi:  15nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132755(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(2-methoxy-benzyl...)
Affinity DataKi:  20nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128007(1-(2,6-difluoro-benzyl)-5-(2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  24nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140102(3-((S)-2-Benzylamino-propyl)-1-(2,6-difluoro-benzy...)
Affinity DataKi:  25nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140111((R)-1-(2,6-difluorobenzyl)-3-(1-(2-methoxybenzylam...)
Affinity DataKi:  30nMAssay Description:In vivo inhibition of monkey Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132728(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  34nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128012(5-Benzo[1,3]dioxol-5-yl-1-(2,6-difluoro-benzyl)-6-...)
Affinity DataKi:  38nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140110((R)-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyph...)
Affinity DataKi:  43nMAssay Description:In vivo inhibition of monkey Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140103((S)-1-(2,6-difluorobenzyl)-3-(2-(cyclopentylamino)...)
Affinity DataKi:  50nMAssay Description:In vivo inhibition of monkey Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132746(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  70nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132761(3-((R)-2-Benzylamino-1-methyl-ethyl)-1-(2,6-difluo...)
Affinity DataKi:  75nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132745(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  79nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140105(1-(2,6-Difluoro-benzyl)-5-(2-fluoro-phenyl)-6-meth...)
Affinity DataKi:  81nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140101(3-[2-((S)-Cyclobutylamino)-propyl]-1-(2,6-difluoro...)
Affinity DataKi:  87nMAssay Description:In vivo inhibition of monkey Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140098(1-(2,6-Difluoro-benzyl)-5-(2-fluoro-3-methoxy-phen...)
Affinity DataKi:  87nMAssay Description:In vivo inhibition of monkey Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140118(1-(2,6-Difluoro-benzyl)-5-(4-isopropyl-phenyl)-6-m...)
Affinity DataKi:  110nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140100(1-(2,6-Difluoro-benzyl)-6-methyl-3-{2-[methyl-(2-p...)
Affinity DataKi:  120nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132721(3-((R)-2-Benzylamino-propyl)-1-(2,6-difluoro-benzy...)
Affinity DataKi:  130nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132723(3-((S)-2-Benzylamino-propyl)-1-(2,6-difluoro-benzy...)
Affinity DataKi:  140nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140119(5-Dibenzofuran-2-yl-1-(2,6-difluoro-benzyl)-6-meth...)
Affinity DataKi:  170nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140109(1-(2,6-Difluoro-benzyl)-3-[(S)-2-(1-ethyl-propylam...)
Affinity DataKi:  200nMAssay Description:In vivo inhibition of monkey Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140108(1-(2,6-Difluoro-benzyl)-6-methyl-3-{2-[methyl-(2-p...)
Affinity DataKi:  220nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128009(1-(2,6-Difluoro-benzyl)-5-(4-methoxy-phenyl)-6-met...)
Affinity DataKi:  230nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140107(1-(2,6-Difluoro-benzyl)-5-(3-isopropyl-phenyl)-6-m...)
Affinity DataKi:  240nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132747(1-(2,6-Difluoro-benzyl)-3-[(S)-2-(2-methoxy-benzyl...)
Affinity DataKi:  320nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140106(1-(2,6-Difluoro-benzyl)-6-methyl-3-{2-[methyl-(2-p...)
Affinity DataKi:  340nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132763(3-((S)-2-Benzylamino-1-methyl-ethyl)-1-(2,6-difluo...)
Affinity DataKi:  370nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50140121(5-(3-Chloro-phenyl)-1-(2,6-difluoro-benzyl)-6-meth...)
Affinity DataKi:  370nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132767(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  400nMAssay Description:Binding affinity evaluated by the ability to inhibit des-Gly10[125I]Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]- Gonadotropin-releasing hormone binding to cloned h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
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