Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50014094
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM227589(Radicicol)
Affinity DataIC50: 200nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15384(PUZ | 8-(2,5-dimethoxybenzyl)-2-fluoro-9-pent-4-yn...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15359(17AAG | Tanespimycin | GLD-36 | (4E,6Z,8S,9S,10E,1...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15383(PU0 | 9-butyl-8-[(2,5-dimethoxyphenyl)methyl]-2-fl...)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15377(PU6 | CHEMBL326564 | 8-(2H-1,3-benzodioxol-5-ylmet...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15385(8-(1,3-benzodioxol-5-ylmethyl)-9-butyl-2-fluoro-9H...)
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15381(8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-2-fluo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15378(PU7 | 9-butyl-8-(2,5-dimethoxybenzyl)-9H-purin-6-a...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15382(8-[(2,5-dimethoxyphenyl)methyl]-2-fluoro-7H-purin-...)
Affinity DataIC50: 5.35E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15376(CHEMBL109612 | PU5 | 9-butyl-8-(3-methoxybenzyl)-9...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15375(CHEMBL112834 | 9-butyl-8-(4-methoxybenzyl)-9H-puri...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15380(CHEMBL326523 | PU9 | 8-[(2-chloro-3,4,5-trimethoxy...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15374(CHEMBL113690 | 9-butyl-8-(3,4,5-trimethoxybenzyl)-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15379(CHEMBL112896 | PU8 | 9-butyl-8-[(2-chloro-3,4,5-tr...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)