Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50000295
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataKi:  65nMAssay Description:Compound was evaluated for its ability to displace [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004109(CHEMBL142577 | 1-(2-Phenyl-bicyclo[3.1.0]hex-2-yl)...)
Affinity DataKi:  582nMAssay Description:Compound was evaluated for its ability to displace [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004111(CHEMBL343429 | 1-(3-Phenyl-bicyclo[3.1.0]hex-3-yl)...)
Affinity DataKi:  644nMAssay Description:Compound was evaluated for its ability to displace [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004113(CHEMBL347761 | 1-(3-Phenyl-bicyclo[3.1.0]hex-3-yl)...)
Affinity DataKi:  711nMAssay Description:Compound was evaluated for its ability to displace [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataKi:  1.09E+3nMAssay Description:Compound was evaluated for its ability to displace [3H](+)-pentazocine from sigma receptor in Guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004112(CHEMBL358455 | 1-(2-Phenyl-bicyclo[3.1.0]hex-2-yl)...)
Affinity DataKi:  1.13E+3nMAssay Description:Compound was evaluated for its ability to displace [3H](+)-pentazocine from sigma receptor in Guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004113(CHEMBL347761 | 1-(3-Phenyl-bicyclo[3.1.0]hex-3-yl)...)
Affinity DataKi:  3.72E+3nMAssay Description:Compound was evaluated for its ability to displace [3H](+)-pentazocine from sigma receptor in Guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004109(CHEMBL142577 | 1-(2-Phenyl-bicyclo[3.1.0]hex-2-yl)...)
Affinity DataKi:  4.45E+3nMAssay Description:Compound was evaluated for its ability to displace [3H](+)-pentazocine from sigma receptor in Guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004110(CHEMBL356855 | 1-(2-Phenyl-bicyclo[3.1.0]hex-2-yl)...)
Affinity DataKi:  7.28E+3nMAssay Description:Compound was evaluated for its ability to displace [3H](+)-pentazocine from sigma receptor in Guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004112(CHEMBL358455 | 1-(2-Phenyl-bicyclo[3.1.0]hex-2-yl)...)
Affinity DataKi:  8.22E+3nMAssay Description:Compound was evaluated for its ability to displace [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004111(CHEMBL343429 | 1-(3-Phenyl-bicyclo[3.1.0]hex-3-yl)...)
Affinity DataKi:  1.63E+4nMAssay Description:Compound was evaluated for its ability to displace [3H](+)-pentazocine from sigma receptor in Guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004110(CHEMBL356855 | 1-(2-Phenyl-bicyclo[3.1.0]hex-2-yl)...)
Affinity DataKi:  2.90E+4nMAssay Description:Compound was evaluated for its ability to displace [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed