Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50035376
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50:  678nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(SR-14135 | 1-((2S,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(SR-14138 | 1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahyd...)
Affinity DataEC50:  165nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(SR-14136 | 1-((2R,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataEC50:  65nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(SR-14136 | 1-((2R,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataEC50:  198nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(SR-14137 | 1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahyd...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(SR-14137 | 1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahyd...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(SR-14138 | 1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahyd...)
Affinity DataEC50:  105nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor mu 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(SR-14135 | 1-((2S,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(SR-14135 | 1-((2S,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM21842(OFQ 1-17 | N/OFQ | (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)
Affinity DataEC50:  4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human NOP receptor in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50:  21nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(SR-14136 | 1-((2R,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataEC50:  4.70nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(SR-14137 | 1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahyd...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(SR-14138 | 1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahyd...)
Affinity DataEC50:  210nMAssay Description:Concentration required to stimulate [35S]GTP-gamma-S, binding to human opioid receptor kappa 1 in cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137562(1-(1-Benzyl-piperidin-4-yl)-1,3-dihydro-benzoimida...)
Affinity DataIC50: 200nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM21842(OFQ 1-17 | N/OFQ | (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)
Affinity DataKi:  0.0600nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137564(1'-(4-isopropylcyclohexyl)-2-methyl-5-phenyl-(3aR,...)
Affinity DataKi:  0.490nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(SR-14136 | 1-((2R,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(SR-14138 | 1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahyd...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(SR-14136 | 1-((2R,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataKi:  5.20nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(SR-14136 | 1-((2R,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataKi:  5.70nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(SR-14137 | 1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahyd...)
Affinity DataKi:  18nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(SR-14138 | 1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahyd...)
Affinity DataKi:  20nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(SR-14138 | 1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahyd...)
Affinity DataKi:  23nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  29nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  47nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(SR-14135 | 1-((2S,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataKi:  48nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  119nMAssay Description:Binding affinity for human opioid receptor mu 1 using [3H]- DAMGO as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  189nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  227nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(SR-14135 | 1-((2S,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataKi:  271nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(SR-14137 | 1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahyd...)
Affinity DataKi:  535nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(SR-14135 | 1-((2S,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataKi:  786nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(SR-14137 | 1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahyd...)
Affinity DataKi:  987nMAssay Description:Binding affinity for human opioid receptor kappa 1 using [3H]- U-69,593 as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137566(SR-14138 | 1-Ethyl-3-((2R,6S,9aR)-6-phenyl-octahyd...)
Affinity DataKi:  1.49E+3nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137565(SR-14136 | 1-((2R,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataKi:  1.72E+3nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137563(SR-14137 | 1-Ethyl-3-((2S,6S,9aR)-6-phenyl-octahyd...)
Affinity DataKi:  1.84E+3nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137567(1-((2R,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi:  2.08E+3nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137561(SR-14135 | 1-((2S,6S,9aR)-6-Phenyl-octahydro-quino...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50137568(1-((2S,6S,9aR)-6-Cyclohexyl-octahydro-quinolizin-2...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for human opioid receptor delta 1 using [3H]- CL-DPDPE as radioligand transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed