Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50000282
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  5.20nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataEC50:  35nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  10nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataEC50:  43nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 5.20nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 10nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 15nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 17nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 20nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 24nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 33nMAssay Description:Binding affinity against 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 49nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 60nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 81nMAssay Description:Binding affinity against 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 140nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 250nMAssay Description:Binding affinity against 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 420nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 550nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 680nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 730nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 830nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 1.90E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 3.60E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 5.80E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 8.40E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed