Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50000231
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003237(2,2-Dimethyl-butyric acid 2-(1-hydroxy-ethyl)-8-[2...)
Affinity DataIC50: 7.60nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003236(2,2-Dimethyl-butyric acid 2-hydroxymethyl-8-[2-(4-...)
Affinity DataIC50: 11nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003240(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 12nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003239(2,2-Dimethyl-butyric acid 2-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50: 13nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003235(CHEMBL333443 | BDBM50226269 | 2-Methyl-butyric aci...)
Affinity DataIC50: 18nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003241(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 20nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011036(2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50: 28nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed