Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50000213
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 11nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003039(CHEMBL27173 | 2-(3,7,8,9-Tetrahydro-pyrano[3,2-e]i...)
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003037(CHEMBL25800 | 2-(3-Methyl-3,7,8,9-tetrahydro-pyran...)
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003039(CHEMBL27173 | 2-(3,7,8,9-Tetrahydro-pyrano[3,2-e]i...)
Affinity DataIC50: 41nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1C receptor in pig choroid plexus using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 49nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003036(CHEMBL412876 | Dimethyl-[2-(3,7,8,9-tetrahydro-pyr...)
Affinity DataIC50: 63nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50: 81nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1C receptor in pig choroid plexus using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003037(CHEMBL25800 | 2-(3-Methyl-3,7,8,9-tetrahydro-pyran...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1C receptor in pig choroid plexus using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003039(CHEMBL27173 | 2-(3,7,8,9-Tetrahydro-pyrano[3,2-e]i...)
Affinity DataIC50: 110nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 130nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003036(CHEMBL412876 | Dimethyl-[2-(3,7,8,9-tetrahydro-pyr...)
Affinity DataIC50: 150nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1C receptor in pig choroid plexus using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003036(CHEMBL412876 | Dimethyl-[2-(3,7,8,9-tetrahydro-pyr...)
Affinity DataIC50: 220nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 250nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1C receptor using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003039(CHEMBL27173 | 2-(3,7,8,9-Tetrahydro-pyrano[3,2-e]i...)
Affinity DataIC50: 610nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003037(CHEMBL25800 | 2-(3-Methyl-3,7,8,9-tetrahydro-pyran...)
Affinity DataIC50: 800nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 920nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 1.80E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003036(CHEMBL412876 | Dimethyl-[2-(3,7,8,9-tetrahydro-pyr...)
Affinity DataIC50: 1.90E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003036(CHEMBL412876 | Dimethyl-[2-(3,7,8,9-tetrahydro-pyr...)
Affinity DataIC50: 1.90E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003039(CHEMBL27173 | 2-(3,7,8,9-Tetrahydro-pyrano[3,2-e]i...)
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 2.50E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1C receptor in pig choroid plexus using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003037(CHEMBL25800 | 2-(3-Methyl-3,7,8,9-tetrahydro-pyran...)
Affinity DataIC50: 4.20E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003037(CHEMBL25800 | 2-(3-Methyl-3,7,8,9-tetrahydro-pyran...)
Affinity DataIC50: 5.30E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50: 5.40E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003040(CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...)
Affinity DataIC50: 5.90E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50: 9.30E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed