Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50000178
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002471(CHEMBL289923 | 5-Amino-2-{4-[(2-amino-4-oxo-2,3,4,...)
Affinity DataKi:  64nMAssay Description:Potent inhibitor of Folyl-polyglutamate synthase obtained from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002471(CHEMBL289923 | 5-Amino-2-{4-[(2-amino-4-oxo-2,3,4,...)
Affinity DataKi:  1.40E+3nMAssay Description:potent inhibitor of GAR Tfase obtained from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002473(CHEMBL41743 | 5-Amino-2-{4-[(2-amino-4-oxo-3,4-dih...)
Affinity DataKi:  5.90E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(CHEMBL288142 | 5-Amino-2-{4-[(2-amino-5-chloro-4-o...)
Affinity DataKi:  8.30E+3nMAssay Description:Compound was evaluated for its binding affinity against hog liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed