Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50000112
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataIC50: 0.360nMAssay Description:Antagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataIC50: 0.800nMAssay Description:Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataIC50: 4.70nMAssay Description:Concentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataIC50: 9nMAssay Description:Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 12nMAssay Description:Antagonistic activity against human polymorphonuclear (PMN) LTB4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001610(CHEMBL14823 | CGS 24115 | 7-[3-(4-Acetyl-3-methoxy...)
Affinity DataIC50: 300nMAssay Description:Concentration inhibiting the binding of [3H]LTB4 to human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001612(CHEMBL137121 | 2-(4-Benzyloxy-cyclohexa-1,3-dienyl...)
Affinity DataIC50: 4.70E+3nMAssay Description:Antagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataKi:  0.140nMAssay Description:Affinity for guinea pig PMN LTB-4 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001609(CHEMBL328712 | 8-Benzyloxy-4-[(methyl-phenethyl-ca...)
Affinity DataKi:  2nMAssay Description:Affinity for human PMN LTB-4 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed