Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50000023
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000366(CHEMBL168066 | Acetic acid 1-(2-amino-ethyl)-4-(4-...)
Affinity DataKd:  120nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000340(CHEMBL165086 | 7-Bromo-1-(2-dimethylamino-ethyl)-6...)
Affinity DataKd:  120nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000376(CHEMBL349193 | 1-(2-Dimethylamino-ethyl)-3-ethyl-4...)
Affinity DataKd:  600nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000372(CHEMBL351235 | 1-(2-Dimethylamino-ethyl)-3-hydroxy...)
Affinity DataKd:  660nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000383(CHEMBL98189 | 1-(2-Dimethylamino-ethyl)-4-(4-metho...)
Affinity DataKd:  650nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000355(CHEMBL167512 | 1-(2-Dimethylamino-ethyl)-4-(4-hydr...)
Affinity DataKd:  1.60E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000378(CHEMBL167147 | Acetic acid 4-(4-methoxy-phenyl)-1-...)
Affinity DataKd:  1.80E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000384(CHEMBL165217 | Acetic acid 1-(2-dimethylamino-ethy...)
Affinity DataKd:  1.80E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000359(CHEMBL167987 | 1-(2-Dimethylamino-1-methyl-ethyl)-...)
Affinity DataKd:  540nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000369(CHEMBL89099 | Acetic acid 1-(2-dimethylamino-ethyl...)
Affinity DataKd:  5.10E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000359(CHEMBL167987 | 1-(2-Dimethylamino-1-methyl-ethyl)-...)
Affinity DataKd:  540nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000379(CHEMBL353566 | 1-[2-(Isopropyl-methyl-amino)-ethyl...)
Affinity DataKd:  130nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000388(CHEMBL163771 | Acetic acid 4-(4-methoxy-phenyl)-1-...)
Affinity DataKd:  220nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000353(CHEMBL163740 | 3-Allyl-1-(2-dimethylamino-ethyl)-4...)
Affinity DataKd:  52nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000398(CHEMBL164917 | 3-Acetoxy-1-(2-dimethylamino-ethyl)...)
Affinity DataKd:  1.40E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000387(CHEMBL164399 | Acetic acid 4-(4-methoxy-phenyl)-1-...)
Affinity DataKd:  160nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000389(1-(2-Dimethylamino-ethyl)-4-(4-methoxy-phenyl)-3-m...)
Affinity DataKd:  75nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000380(CHEMBL354933 | Acetic acid 1-(2-dimethylamino-ethy...)
Affinity DataKd:  1.60E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000344(CHEMBL164346 | Acetic acid 4-(4-methoxymethoxy-phe...)
Affinity DataKd:  1.55E+5nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000361(CHEMBL410539 | 4-(3,4-Dimethoxy-phenyl)-1-(2-dimet...)
Affinity DataKd:  2.00E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000337(CHEMBL165049 | 1-(2-Dimethylamino-ethyl)-4-(4-ethy...)
Affinity DataKd:  1.00E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000339(CHEMBL164760 | Acetic acid 4-[4-(2-methoxy-ethoxy)...)
Affinity DataKd:  5.80E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000341(CHEMBL168099 | 1-(2-Dimethylamino-ethyl)-6-methoxy...)
Affinity DataKd:  400nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000342(CHEMBL348940 | Acetic acid 7-chloro-1-(2-dimethyla...)
Affinity DataKd:  5.80E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000343(CHEMBL351402 | Acetic acid 4-(4-methoxy-phenyl)-1-...)
Affinity DataKd:  1.50E+4nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000345(CHEMBL349753 | 1-(2-Dimethylamino-propyl)-4-(4-met...)
Affinity DataKd:  320nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000346(CHEMBL165444 | Acetic acid 4-(4-methoxy-phenyl)-1-...)
Affinity DataKd:  520nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000351(CHEMBL352750 | {2-[4-(4-Methoxy-phenyl)-3-methyl-2...)
Affinity DataKd:  840nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000358(CHEMBL354353 | Acetic acid 7-chloro-1-(2-dimethyla...)
Affinity DataKd:  3.50E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000338(CHEMBL355684 | 1-(2-Dimethylamino-ethyl)-3-methyl-...)
Affinity DataKd:  570nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000357(Acetic acid 7-chloro-1-(2-dimethylamino-ethyl)-4-(...)
Affinity DataKd:  1.40E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000362(CHEMBL349140 | Acetic acid 1-(2-dimethylamino-ethy...)
Affinity DataKd:  1.20E+4nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000363(CHEMBL167384 | 1-(2-Dimethylamino-ethyl)-3-methyl-...)
Affinity DataKd:  1.10E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000350(CHEMBL163719 | 3-Acetoxy-1-(2-dimethylamino-ethyl)...)
Affinity DataKd:  2.00E+3nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000365(CHEMBL350321 | 1-(2-Dimethylamino-ethyl)-4-(4-meth...)
Affinity DataKd:  250nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000373(CHEMBL164134 | Acetic acid 1-[2-(allyl-methyl-amin...)
Affinity DataKd:  420nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000374(CHEMBL353757 | Acetic acid 7-bromo-1-(2-dimethylam...)
Affinity DataKd:  120nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000367(CHEMBL165445 | N-{2-[3-Hydroxy-4-(4-methoxy-phenyl...)
Affinity DataKd:  1.30E+4nMAssay Description:In vitro ability to displace the specific binding of [3H]diltiazem to diltiazem receptor in guinea pig skeletal muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed