Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50013606
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132465(5-{(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-...)
Affinity DataKi:  160nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132460(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132467(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(1-carb...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132465(5-{(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-...)
Affinity DataKi:  1.97E+3nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132462(5-{(S)-2-tert-Butoxycarbonylamino-2-[4-(2-methoxyc...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132466(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132468(2-(4-{2-tert-Butoxycarbonylamino-3-[4-(carboxy-cyc...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132460(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132467(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(1-carb...)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132469(2-(2-carboxy-4-{2-[4-(3-hydroxy-2-methyloxycarbony...)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132464(2-(4-{2-tert-Butoxycarbonylamino-3-[4-(carbamoyl-c...)
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132463(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi:  1.52E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132466(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi:  1.67E+4nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi:  2.48E+4nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132465(5-{(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against Cell division cycle 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132465(5-{(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against CD45 PhosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132460(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against Tyrosine phosphatase SHP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against CD45 PhosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132465(5-{(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against Tyrosine phosphatase SHP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against Cell division cycle 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132460(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against CD45 PhosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against LARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132462(5-{(S)-2-tert-Butoxycarbonylamino-2-[4-(2-methoxyc...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132465(5-{(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against LARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132460(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against Cell division cycle 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against Tyrosine phosphatase SHP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132460(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against LARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132459(5-{2-tert-Butoxycarbonylamino-2-[4-(2-methoxycarbo...)
Affinity DataKi:  4.86E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132464(2-(4-{2-tert-Butoxycarbonylamino-3-[4-(carbamoyl-c...)
Affinity DataKi:  7.95E+4nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132463(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi:  9.78E+4nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132469(2-(2-carboxy-4-{2-[4-(3-hydroxy-2-methyloxycarbony...)
Affinity DataKi:  1.29E+5nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132458(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132458(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132468(2-(4-{2-tert-Butoxycarbonylamino-3-[4-(carboxy-cyc...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13986(CHEMBL106109 | 2-{4-[(2S)-2-{[(tert-butoxy)carbony...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13986(CHEMBL106109 | 2-{4-[(2S)-2-{[(tert-butoxy)carbony...)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132459(5-{2-tert-Butoxycarbonylamino-2-[4-(2-methoxycarbo...)
Affinity DataKi:  2.73E+5nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed