Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50013602
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132386((6,7-Dimethoxy-quinoxalin-2-yl)-phenyl-amine | CHE...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132406(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-2-methyl-cy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132405(5-(6,7-Dimethoxy-quinoxalin-2-ylamino)-bicyclo[2.2...)
Affinity DataIC50: 24nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132409(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132395((6,7-Dimethoxy-quinoxalin-2-yl)-(3-methyl-cyclohex...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132409(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50: 49nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132407(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexano...)
Affinity DataIC50: 68nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 76nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132399(Cyclohexyl-(6,7-dimethoxy-quinoxalin-2-yl)-amine |...)
Affinity DataIC50: 124nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 299nMAssay Description:Inhibition of Mitogenesis, PDGF-AA, assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132409(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50: 345nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 353nMAssay Description:Inhibition of Mitogenesis, PDGF-BB, assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039082(6,7-Dimethoxy-3-thiophen-3-yl-quinoline | RPR-1015...)
Affinity DataIC50: 461nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132404(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50: 930nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132408(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10/8/9(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of JNK, c-Jun N-terminal kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Janus kinase 3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Janus kinase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed