Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 1985
LigandPNGBDBM15819(1:1 mixture of diastereomers | CHEMBL55243 | 2-[(4...)
Affinity DataKi:  76nM ΔG°:  -40.2kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15817(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  120nM ΔG°:  -39.1kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15818(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  130nM ΔG°:  -38.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15812(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  140nM ΔG°:  -38.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15812(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  160nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15817(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  240nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15813(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(S)-...)
Affinity DataKi:  250nM ΔG°:  -37.3kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15815(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  270nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15813(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(S)-...)
Affinity DataKi:  290nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15815(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  330nM ΔG°:  -36.6kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15820(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  370nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15819(1:1 mixture of diastereomers | CHEMBL55243 | 2-[(4...)
Affinity DataKi:  380nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15814(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  400nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15814(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  430nM ΔG°:  -36.0kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15806(2-{[4-(2-acetamido-2-{[(4-nitrophenyl)methyl]carba...)
Affinity DataKi:  450nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15820(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  470nM ΔG°:  -35.8kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15818(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  510nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15821(1:1 mixture of diastereomers | 2-[(4-{2-acetamido-...)
Affinity DataKi:  540nM ΔG°:  -35.4kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15806(2-{[4-(2-acetamido-2-{[(4-nitrophenyl)methyl]carba...)
Affinity DataKi:  540nM ΔG°:  -35.4kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15821(1:1 mixture of diastereomers | 2-[(4-{2-acetamido-...)
Affinity DataKi:  670nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15811(2-({4-[2-({4-[(1-carbamoyl-2-phenylethyl)carbamoyl...)
Affinity DataKi:  700nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15816(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  710nM ΔG°:  -34.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15816(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  820nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13971(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]-2-eth...)
Affinity DataKi:  900nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15822(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1R)...)
Affinity DataKi:  1.00E+3nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM13971(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]-2-eth...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15807(2-{[4-(2-{[(4-chlorophenyl)methyl]carbamoyl}-2-ace...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15811(2-({4-[2-({4-[(1-carbamoyl-2-phenylethyl)carbamoyl...)
Affinity DataKi:  1.30E+3nM ΔG°:  -33.3kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15810(2-({4-[2-acetamido-2-({4-[(2-phenylethyl)carbamoyl...)
Affinity DataKi:  1.40E+3nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15807(2-{[4-(2-{[(4-chlorophenyl)methyl]carbamoyl}-2-ace...)
Affinity DataKi:  1.50E+3nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15822(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1R)...)
Affinity DataKi:  1.70E+3nM ΔG°:  -32.6kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15809(1:1 racemic mixture | 2-[(4-{2-[(4-carboxybutyl)ca...)
Affinity DataKi:  2.20E+3nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15809(1:1 racemic mixture | 2-[(4-{2-[(4-carboxybutyl)ca...)
Affinity DataKi:  2.50E+3nM ΔG°:  -31.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15810(2-({4-[2-acetamido-2-({4-[(2-phenylethyl)carbamoyl...)
Affinity DataKi:  3.40E+3nM ΔG°:  -30.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM15808(1:1 racemic mixture | 2-{[4-(2-acetamido-2-{[(4-me...)
Affinity DataKi:  3.60E+3nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM15808(1:1 racemic mixture | 2-{[4-(2-acetamido-2-{[(4-me...)
Affinity DataKi:  4.70E+3nM ΔG°:  -30.1kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
LigandPNGBDBM13951(CHEMBL65459 | 2-[(2,3-dimethylphenyl)amidoformic a...)
Affinity DataKi:  9.30E+4nM ΔG°:  -22.8kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed