Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50012976
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataKd:  94nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124885(N-(2-methoxybenzyl)cinnamamidine | (E)-N-(2-Methox...)
Affinity DataKd:  1nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124908(N-(2-Methoxy-benzyl)-4-trifluoromethoxy-benzamidin...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124909(N-(3,5-Dimethyl-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124923(N-(3,5-Dimethyl-benzyl)-4-trifluoromethyl-benzamid...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124917(N-(3-Methoxy-benzyl)-4-trifluoromethoxy-benzamidin...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124914(N-(3,5-Dichloro-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataIC50: 24nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124921(N-(3-Chloro-benzyl)-4-trifluoromethyl-benzamidine ...)
Affinity DataIC50: 32nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124915(N-Benzyl-4-trifluoromethoxy-benzamidine | CHEMBL16...)
Affinity DataIC50: 46nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)
Affinity DataIC50: 47nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124920(N-(2-Chloro-benzyl)-4-trifluoromethyl-benzamidine ...)
Affinity DataIC50: 48nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124918(3,4-Dichloro-N-(2-trifluoromethoxy-benzyl)-benzami...)
Affinity DataIC50: 57nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124919(3,4-Dichloro-N-(3-chloro-benzyl)-benzamidine | CHE...)
Affinity DataIC50: 110nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124922(4-Chloro-N-(3-chloro-benzyl)-benzamidine | CHEMBL1...)
Affinity DataIC50: 160nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124926(N-Benzyl-4-trifluoromethyl-benzamidine | CHEMBL159...)
Affinity DataIC50: 360nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124911(3-Chloro-N-(3-chloro-benzyl)-benzamidine | CHEMBL1...)
Affinity DataIC50: 420nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124912(N-(3-Chloro-benzyl)-4-fluoro-benzamidine | CHEMBL1...)
Affinity DataIC50: 450nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124925(4-Trifluoromethyl-N-(3-trifluoromethyl-benzyl)-ben...)
Affinity DataIC50: 660nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124916(N-Benzyl-4-chloro-benzamidine | CHEMBL161977)
Affinity DataIC50: 720nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2A subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124909(N-(3,5-Dimethyl-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2A subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124918(3,4-Dichloro-N-(2-trifluoromethoxy-benzyl)-benzami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2A subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124919(3,4-Dichloro-N-(3-chloro-benzyl)-benzamidine | CHE...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2A subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124914(N-(3,5-Dichloro-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2A subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124914(N-(3,5-Dichloro-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124885(N-(2-methoxybenzyl)cinnamamidine | (E)-N-(2-Methox...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124909(N-(3,5-Dimethyl-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataKi:  1.20nMAssay Description:Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124923(N-(3,5-Dimethyl-benzyl)-4-trifluoromethyl-benzamid...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124908(N-(2-Methoxy-benzyl)-4-trifluoromethoxy-benzamidin...)
Affinity DataKi:  5.70nMAssay Description:Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124892((E)-N-Benzyl-3-phenyl-acrylamidine | CHEMBL158874)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124918(3,4-Dichloro-N-(2-trifluoromethoxy-benzyl)-benzami...)
Affinity DataKi:  12nMAssay Description:Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124919(3,4-Dichloro-N-(3-chloro-benzyl)-benzamidine | CHE...)
Affinity DataKi:  16nMAssay Description:Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124921(N-(3-Chloro-benzyl)-4-trifluoromethyl-benzamidine ...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124917(N-(3-Methoxy-benzyl)-4-trifluoromethoxy-benzamidin...)
Affinity DataKi:  23nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124920(N-(2-Chloro-benzyl)-4-trifluoromethyl-benzamidine ...)
Affinity DataKi:  56nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124922(4-Chloro-N-(3-chloro-benzyl)-benzamidine | CHEMBL1...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)
Affinity DataKi:  72nMAssay Description:Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124915(N-Benzyl-4-trifluoromethoxy-benzamidine | CHEMBL16...)
Affinity DataKi:  120nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124926(N-Benzyl-4-trifluoromethyl-benzamidine | CHEMBL159...)
Affinity DataKi:  480nMAssay Description:Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124912(N-(3-Chloro-benzyl)-4-fluoro-benzamidine | CHEMBL1...)
Affinity DataKi:  600nMAssay Description:Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124925(4-Trifluoromethyl-N-(3-trifluoromethyl-benzyl)-ben...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124911(3-Chloro-N-(3-chloro-benzyl)-benzamidine | CHEMBL1...)
Affinity DataKi:  800nMAssay Description:Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124916(N-Benzyl-4-chloro-benzamidine | CHEMBL161977)
Affinity DataKi:  970nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124913(N-(4-Methoxy-benzyl)-4-trifluoromethoxy-benzamidin...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124924(N-Benzyl-biphenyl-4-carboxamidine | CHEMBL349067)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124930(N-(3-Chloro-benzyl)-3-fluoro-benzamidine | CHEMBL3...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124910(N-Benzyl-4-methanesulfonyl-benzamidine | CHEMBL159...)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124927(2-Chloro-N-(3-chloro-benzyl)-benzamidine | CHEMBL3...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124929(N-(3-Chloro-benzyl)-benzamidine | CHEMBL159498)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124928(N-(3-Chloro-benzyl)-2-fluoro-benzamidine | CHEMBL1...)
Affinity DataKi: >1.50E+4nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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