Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 12181
TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684673(US20240228460, Compound (102) | US20240228460, Com...)
Affinity DataIC50: 1.60E+3nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684672(US20240228460, Compound (101))
Affinity DataIC50: 1.70E+3nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684678(US20240228460, Compound (106))
Affinity DataIC50: 8.90E+3nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProcathepsin L(Human)
Variational AI

US Patent
LigandPNGBDBM684678(US20240228460, Compound (106))
Affinity DataIC50: 1.02E+4nMAssay Description:Assays to evaluate the inhibition of cathepsin L contained 25 pM cathepsin L (RD systems: 952-CY-010), 5 uM Z-LR-AMC fluorogenic peptide substrate, 1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684679(US20240228460, Compound (107))
Affinity DataIC50: 1.92E+4nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684680(US20240228460, Compound (108))
Affinity DataIC50: 3.22E+4nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProcathepsin L(Human)
Variational AI

US Patent
LigandPNGBDBM684673(US20240228460, Compound (102) | US20240228460, Com...)
Affinity DataIC50: 3.68E+4nMAssay Description:Assays to evaluate the inhibition of cathepsin L contained 25 pM cathepsin L (RD systems: 952-CY-010), 5 uM Z-LR-AMC fluorogenic peptide substrate, 1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProcathepsin L(Human)
Variational AI

US Patent
LigandPNGBDBM684673(US20240228460, Compound (102) | US20240228460, Com...)
Affinity DataIC50: 4.78E+4nMAssay Description:Assays to evaluate the inhibition of cathepsin L contained 25 pM cathepsin L (RD systems: 952-CY-010), 5 uM Z-LR-AMC fluorogenic peptide substrate, 1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684676(US20240228460, Compound (104))
Affinity DataIC50: 4.78E+4nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684677(US20240228460, Compound (105))
Affinity DataIC50: 6.13E+4nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684673(US20240228460, Compound (102) | US20240228460, Com...)
Affinity DataIC50: 7.12E+4nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProcathepsin L(Human)
Variational AI

US Patent
LigandPNGBDBM684672(US20240228460, Compound (101))
Affinity DataIC50: 1.00E+5nMAssay Description:Assays to evaluate the inhibition of cathepsin L contained 25 pM cathepsin L (RD systems: 952-CY-010), 5 uM Z-LR-AMC fluorogenic peptide substrate, 1...More data for this Ligand-Target Pair
In DepthDetails
US Patent