Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50012211
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116165((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1-pyridin-3-y...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116164((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-(2-methoxy-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116179((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1-pyridin-3-y...)
Affinity DataIC50: 17nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116176((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-(1-methyl-6...)
Affinity DataIC50: 18nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116172((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-(4-methyl-p...)
Affinity DataIC50: 22nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116162((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-(6-oxo-1,6-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116181((S)-2-[(1'-Acetyl-2',3',5',6'-tetrahydro-1'H-[3,4'...)
Affinity DataIC50: 30nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116184((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1-pyridazin-4...)
Affinity DataIC50: 33nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116167((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-(6-methyl-p...)
Affinity DataIC50: 36nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116191((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-(2-methyl-p...)
Affinity DataIC50: 44nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116174((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1-pyridin-4-y...)
Affinity DataIC50: 49nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116161((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1'-methyl-2',...)
Affinity DataIC50: 51nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116166((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(2',3',5',6'-t...)
Affinity DataIC50: 83nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116194((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(3-methyl-1-py...)
Affinity DataIC50: 94nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116154((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(4-pyridin-3-y...)
Affinity DataIC50: 94nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116177((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1-quinolin-3-...)
Affinity DataIC50: 98nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116178((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1-phenyl-cycl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116186((S)-2-[(1-Isoquinolin-4-yl-cyclopentanecarbonyl)-a...)
Affinity DataIC50: 120nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116159((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1-pyridin-3-y...)
Affinity DataIC50: 158nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116157((S)-2-{[1-(5-Bromo-pyridin-3-yl)-cyclopentanecarbo...)
Affinity DataIC50: 165nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116160((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[1-(1-oxy-pyri...)
Affinity DataIC50: 180nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116185((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(1-pyridin-2-y...)
Affinity DataIC50: 215nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed