Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 1063
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50: 390nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8550(2-{[(3-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50: 820nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8555(methyl 3-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]...)
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8541(N-[2-(2-fluorophenyl)ethyl]-2-[4-({[5-(pyridin-4-y...)
Affinity DataIC50: 1.20E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8554(2-{[(3-fluorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50: 1.40E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8548(cid_805390 | 2-(benzylsulfanyl)-5-(pyridin-4-yl)-1...)
Affinity DataIC50: 6.70E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8543(2-[4-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulf...)
Affinity DataIC50: 8.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8542(2-[4-({[5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl]sul...)
Affinity DataIC50: 1.10E+4nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8551(2-{[(2-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50: 1.20E+4nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8549(2-[(2-phenylethyl)sulfanyl]-5-(pyridin-4-yl)-1,3,4...)
Affinity DataIC50: 2.90E+4nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8547(4-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfany...)
Affinity DataIC50: 2.90E+4nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8553(2-{[(4-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50: 1.98E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8556(3-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfany...)
Affinity DataIC50: 2.35E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8546(2-[4-({[5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl]sul...)
Affinity DataIC50: 2.50E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8545(2-[4-({[5-(pyridin-3-yl)-1,3,4-thiadiazol-2-yl]sul...)
Affinity DataIC50: 2.50E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8544(2-[4-({[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sul...)
Affinity DataIC50: 2.50E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandPNGBDBM8557(2-({[3-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]methy...)
Affinity DataIC50: 2.50E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed