Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50011938
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 22nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50: 220nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 420nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50: 440nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112313(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-eth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Escherichia coli thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of Escherichia coli thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112313(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-eth...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of rocombinant human thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of recombinant human thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibition of rh thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed