Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50011720
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50022271(2-(3-benzoylphenyl)propanoic acid | 2-(3-Benzoylph...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of cyclooxygenase-1 via inhibition of TXB2 generation in the presence of 1 uM arachidonic acid in human plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50022271(2-(3-benzoylphenyl)propanoic acid | 2-(3-Benzoylph...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109722(3-(3-Benzoyl-5-ethyl-phenyl)-acrylamide | CHEMBL15...)
Affinity DataIC50: 74nMAssay Description:In vitro inhibition of cyclooxygenase-1 via inhibition of TXB2 generation in the presence of 1 uM arachidonic acid in human plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109719(2-(3-Benzoyl-4-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109719(2-(3-Benzoyl-4-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 770nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 830nMAssay Description:Tested in vitro for inhibition of cyclooxygenase-2 in human blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109716(2-[3-Benzoyl-5-(2-methyl-propenyl)-phenyl]-ethenes...)
Affinity DataIC50: 980nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109726(2-(3-Benzoyl-5-cyano-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109722(3-(3-Benzoyl-5-ethyl-phenyl)-acrylamide | CHEMBL15...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.88E+3nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109717(3-(3-Benzoyl-5-ethyl-phenyl)-acrylic acid | CHEMBL...)
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109716(2-[3-Benzoyl-5-(2-methyl-propenyl)-phenyl]-ethenes...)
Affinity DataIC50: 3.60E+3nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109725(3-(3-Benzoyl-5-ethyl-phenyl)-acrylic acid ethyl es...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109721(2-(3-Benzoyl-5-hydroxymethyl-phenyl)-ethenesulfoni...)
Affinity DataIC50: 5.40E+3nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109726(2-(3-Benzoyl-5-cyano-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 5.60E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109723(2-(4-Benzoyl-2-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 5.60E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109723(2-(4-Benzoyl-2-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 6.30E+3nMAssay Description:In vitro inhibition of cyclooxygenase-1 via inhibition of TXB2 generation in the presence of 1 uM arachidonic acid in human platelets at concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109718(2-(3-Acetyl-5-benzoyl-phenyl)-ethenesulfonic acid ...)
Affinity DataIC50: 6.40E+3nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109727(2-(3-Benzoyl-5-diethylaminomethyl-phenyl)-ethenesu...)
Affinity DataIC50: 7.10E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109728(2-(4-Benzoyl-2-hydroxymethyl-phenyl)-ethenesulfoni...)
Affinity DataIC50: 8.40E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109721(2-(3-Benzoyl-5-hydroxymethyl-phenyl)-ethenesulfoni...)
Affinity DataIC50: 9.70E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109720(2-[3-Benzoyl-5-(2-methanesulfonyl-vinyl)-phenyl]-p...)
Affinity DataIC50: 9.70E+3nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 1.20E+4nMAssay Description:Tested in vitro for inhibition of cyclooxygenase-2 in human blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 1.83E+4nMAssay Description:Tested in vitro for inhibition of cyclooxygenase-1 in human blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109724(2-(3-Benzoyl-4-methyl-phenyl)-ethenesulfonic acid ...)
Affinity DataIC50: 1.90E+4nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109718(2-(3-Acetyl-5-benzoyl-phenyl)-ethenesulfonic acid ...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested in vitro for inhibition of cyclooxygenase-1 in human blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed