Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50011657
Affinity DataIC50: 12nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Antagonism at the 5-hydroxytryptamine 1A receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor was determined in vitro using a [35S]GTP-gamma-S,More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Antagonism at the 5-hydroxytryptamine 1A receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Antagonism at the 5-hydroxytryptamine 1A receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 524nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor was determined in vitro using a [35S]GTP-gamma-S,More data for this Ligand-Target Pair
Affinity DataIC50: 666nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor was determined in vitro using a [35S]GTP-gamma-S,More data for this Ligand-Target Pair
Affinity DataIC50: 684nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor was determined in vitro using a [35S]GTP-gamma-S,More data for this Ligand-Target Pair
Affinity DataIC50: 686nMAssay Description:Antagonism at the 5-hydroxytryptamine 1A receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 969nMAssay Description:Antagonism at the 5-hydroxytryptamine 1A receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Antagonism at the 5-hydroxytryptamine 1A receptor in vitroMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Affinity for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Affinity for HC Serotonin transporter determined in vitro by incubating compound and [3H]5-HT with human carcinoma (Jar cells), previously treated wi...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Affinity for HC Serotonin transporter determined in vitro by incubating compound and [3H]5-HT with human carcinoma (Jar cells), previously treated wi...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Affinity for HC Serotonin transporter determined in vitro by incubating compound and [3H]5-HT with human carcinoma (Jar cells), previously treated wi...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:Affinity for HC Serotonin transporter determined in vitro by incubating compound and [3H]5-HT with human carcinoma (Jar cells), previously treated wi...More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 78nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Affinity for HC Serotonin transporter determined in vitro by incubating compound and [3H]5-HT with human carcinoma (Jar cells), previously treated wi...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 128nMAssay Description:Affinity for HC Serotonin transporter determined in vitro by incubating compound and [3H]5-HT with human carcinoma (Jar cells), previously treated wi...More data for this Ligand-Target Pair
Affinity DataKi: 168nMAssay Description:In vitro binding affinity towards Human 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
