Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50011411
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102780(3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIP...)
Affinity DataKi:  8nMAssay Description:The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106240(6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  9nMAssay Description:The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106239(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  20nMAssay Description:The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102780(3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIP...)
Affinity DataKi:  35nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102780(3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIP...)
Affinity DataKi:  78nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102780(3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIP...)
Affinity DataKi:  100nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  100nMAssay Description:The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106240(6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  110nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102780(3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIP...)
Affinity DataKi:  130nMAssay Description:The compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102780(3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIP...)
Affinity DataKi:  160nMAssay Description:The compound was tested for inhibition of human coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  210nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106240(6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  230nMAssay Description:The compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102780(3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIP...)
Affinity DataKi:  320nMAssay Description:The compound was tested for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106239(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  350nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106241(2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...)
Affinity DataKi:  360nMAssay Description:The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106238(4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  490nMAssay Description:The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106239(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  750nMAssay Description:The compound was tested for inhibition of human coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106239(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  1.10E+3nMAssay Description:The compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106239(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  1.60E+3nMAssay Description:The compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106240(6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  1.70E+3nMAssay Description:The compound was tested for inhibition of human coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106242(6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...)
Affinity DataKi:  2.00E+3nMAssay Description:The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106238(4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  3.00E+3nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106238(4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  3.30E+3nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106239(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  3.60E+3nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106241(2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...)
Affinity DataKi:  3.90E+3nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106238(4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  4.70E+3nMAssay Description:The compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106238(4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  5.20E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106238(4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  5.50E+3nMAssay Description:The compound was tested for inhibition of human coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  7.00E+3nMAssay Description:The compound was tested for inhibition of human coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106239(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  7.50E+3nMAssay Description:The compound was tested for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106240(6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  8.80E+3nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106241(2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...)
Affinity DataKi:  1.40E+4nMAssay Description:The compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106241(2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...)
Affinity DataKi:  1.60E+4nMAssay Description:The compound was tested for inhibition of human coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106241(2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...)
Affinity DataKi:  1.80E+4nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106240(6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  1.90E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106242(6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...)
Affinity DataKi:  1.90E+4nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106241(2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...)
Affinity DataKi:  2.60E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  3.90E+4nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106242(6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...)
Affinity DataKi:  4.60E+4nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106242(6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...)
Affinity DataKi:  5.00E+4nMAssay Description:The compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106240(6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  6.00E+4nMAssay Description:The compound was tested for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106238(4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataKi:  6.50E+4nMAssay Description:The compound was tested for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106242(6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...)
Affinity DataKi: >7.50E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi: >7.50E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106241(2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...)
Affinity DataKi: >7.50E+4nMAssay Description:The compound was tested for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106242(6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...)
Affinity DataKi: >7.50E+4nMAssay Description:The compound was tested for inhibition of human coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106242(6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...)
Affinity DataKi: >7.50E+4nMAssay Description:The compound was tested for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi: >7.50E+4nMAssay Description:The compound was tested for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed