Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50011300
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104843(N-[3-(3-Bromo-4-fluoro-phenyl)-2,2-dimethyl-cyclop...)
Affinity DataIC50: 3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104846(N-[3-(2,5-Dichloro-phenyl)-2,2-dimethyl-cyclopropa...)
Affinity DataIC50: 5nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104848(N-[3-(3-Ethyl-4-fluoro-phenyl)-2,2-dimethyl-cyclop...)
Affinity DataIC50: 5nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104856(N-[3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cyclopropa...)
Affinity DataIC50: 6nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(N-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...)
Affinity DataIC50: 9nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104852(N-[3-(3-Methoxy-phenyl)-2,2-dimethyl-cyclopropanec...)
Affinity DataIC50: 12nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104842(N-[3-(3-Chloro-phenyl)-2,2-dimethyl-cyclopropaneca...)
Affinity DataIC50: 14nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104862(N-[3-(4-Fluoro-3-isopropyl-phenyl)-2,2-dimethyl-cy...)
Affinity DataIC50: 17nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104855(N-[3-(4-Fluoro-3-methyl-phenyl)-2,2-dimethyl-cyclo...)
Affinity DataIC50: 32nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104853(N-[2-(2,5-Dichloro-phenyl)-cyclopropanecarbonyl]-g...)
Affinity DataIC50: 40nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104860(N-(2,2-Dimethyl-3-phenyl-cyclopropanecarbonyl)-gua...)
Affinity DataIC50: 69nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104863(N-[2-(3-Bromo-4-fluoro-phenyl)-cyclopropanecarbony...)
Affinity DataIC50: 90nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104854(N-[2-(2,3-Dihydro-benzofuran-4-yl)-cyclopropanecar...)
Affinity DataIC50: 120nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104861(N-[2-(3-Chloro-phenyl)-cyclopropanecarbonyl]-guani...)
Affinity DataIC50: 280nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 380nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104851(N-[2-(3-Methoxy-phenyl)-cyclopropanecarbonyl]-guan...)
Affinity DataIC50: 540nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104847(N-[2-(2-Chloro-phenyl)-cyclopropanecarbonyl]-guani...)
Affinity DataIC50: 980nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104845(N-[2-(4-Fluoro-phenyl)-cyclopropanecarbonyl]-guani...)
Affinity DataIC50: 1.60E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104858(N-[2-(3-Nitro-phenyl)-cyclopropanecarbonyl]-guanid...)
Affinity DataIC50: 1.60E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(N-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...)
Affinity DataIC50: 1.80E+3nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104859(N-[2-(4-Chloro-phenyl)-cyclopropanecarbonyl]-guani...)
Affinity DataIC50: 2.90E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(N-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...)
Affinity DataIC50: 3.36E+3nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104849(N-(2-Phenyl-cyclopropanecarbonyl)-guanidine | CHEM...)
Affinity DataIC50: 3.50E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 1.70E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-3 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104857(N-[2-(4-Nitro-phenyl)-cyclopropanecarbonyl]-guanid...)
Affinity DataIC50: 3.00E+4nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(N-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-3 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104850(N-[2-(4-Isopropyl-phenyl)-cyclopropanecarbonyl]-gu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-3 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 6.20E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed