Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50010647
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097082(2-(4-Bromo-phenyl)-6-iodo-quinoline-4-carboxylic a...)
Affinity DataIC50: 19nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097095(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 20nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097106(2-(4-Bromo-phenyl)-8-chloro-6-methyl-quinoline-4-c...)
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097105(6-Bromo-2-(4-bromo-phenyl)-quinoline-4-carboxylic ...)
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097090(2-(4-Bromo-phenyl)-6-chloro-quinoline-4-carboxylic...)
Affinity DataIC50: 26nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097086(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 30nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097113(2-(4-Bromo-phenyl)-6-trifluoromethoxy-quinoline-4-...)
Affinity DataIC50: 53nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097102(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 70nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097107(2-(4-Bromo-phenyl)-7-fluoro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 120nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097091(2-(4-Bromo-phenyl)-5,7-dichloro-quinoline-4-carbox...)
Affinity DataIC50: 140nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097093(7-Bromo-2-(4-bromo-phenyl)-8-methyl-quinoline-4-ca...)
Affinity DataIC50: 150nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097104(6-Bromo-2-(4-bromo-phenyl)-8-trifluoromethyl-quino...)
Affinity DataIC50: 220nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097103(2-(4-Bromo-phenyl)-6-(4-hydroxy-phenyl)-quinoline-...)
Affinity DataIC50: 350nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097094(2-(4-Bromo-phenyl)-quinoline-4-carboxylic acid | C...)
Affinity DataIC50: 500nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097087(2-(4-Bromo-phenyl)-6-((E)-2-carboxy-vinyl)-quinoli...)
Affinity DataIC50: 1.30E+3nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097084(2-(4-Bromo-phenyl)-7-chloro-5-methyl-quinoline-4-c...)
Affinity DataIC50: 1.50E+3nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097109(2-(4-Bromo-phenyl)-6-chloro-8-hydroxymethyl-quinol...)
Affinity DataIC50: 1.50E+3nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097111(Sulfamic acid 2-(4-bromo-phenyl)-6-chloro-8-methyl...)
Affinity DataIC50: 2.40E+3nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097099(6-Amino-2-(4-bromo-phenyl)-quinoline-4-carboxylic ...)
Affinity DataIC50: 3.30E+3nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097101(2-Naphthalen-2-yl-quinoline-4-carboxylic acid | CH...)
Affinity DataIC50: 3.60E+3nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097092(2-{[2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline...)
Affinity DataIC50: 5.70E+3nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097108(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 8.80E+3nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097085(2-(4-Bromo-phenyl)-6-sulfo-quinoline-4-carboxylic ...)
Affinity DataIC50: 1.50E+4nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097083(2-(3,4-Dichloro-phenyl)-quinoline-4-carboxylic aci...)
Affinity DataIC50: 1.90E+4nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097106(2-(4-Bromo-phenyl)-8-chloro-6-methyl-quinoline-4-c...)
Affinity DataIC50: 2.00E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 2.00E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097090(2-(4-Bromo-phenyl)-6-chloro-quinoline-4-carboxylic...)
Affinity DataIC50: 2.00E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097105(6-Bromo-2-(4-bromo-phenyl)-quinoline-4-carboxylic ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097088(2-(4-Bromo-phenyl)-6,8-dimethyl-quinoline-4-carbox...)
Affinity DataIC50: 2.50E+4nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097098(CHEMBL153072 | cid_625773 | 2-(5-Chloro-thiophen-2...)
Affinity DataIC50: 3.20E+4nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097103(2-(4-Bromo-phenyl)-6-(4-hydroxy-phenyl)-quinoline-...)
Affinity DataIC50: 3.50E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097104(6-Bromo-2-(4-bromo-phenyl)-8-trifluoromethyl-quino...)
Affinity DataIC50: 5.60E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097107(2-(4-Bromo-phenyl)-7-fluoro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 6.00E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097093(7-Bromo-2-(4-bromo-phenyl)-8-methyl-quinoline-4-ca...)
Affinity DataIC50: 7.00E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097087(2-(4-Bromo-phenyl)-6-((E)-2-carboxy-vinyl)-quinoli...)
Affinity DataIC50: 8.00E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097099(6-Amino-2-(4-bromo-phenyl)-quinoline-4-carboxylic ...)
Affinity DataIC50: 9.50E+4nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097112(2-(4-Methoxy-phenyl)-quinoline-4-carboxylic acid |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097094(2-(4-Bromo-phenyl)-quinoline-4-carboxylic acid | C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097098(CHEMBL153072 | cid_625773 | 2-(5-Chloro-thiophen-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097109(2-(4-Bromo-phenyl)-6-chloro-8-hydroxymethyl-quinol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097113(2-(4-Bromo-phenyl)-6-trifluoromethoxy-quinoline-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097100(2-Phenyl-quinoline-4-carboxylic acid | 2-phenylqui...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097110(2-(4-Trifluoromethyl-phenyl)-quinoline-4-carboxyli...)
Affinity DataIC50: 1.00E+5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097112(2-(4-Methoxy-phenyl)-quinoline-4-carboxylic acid |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097095(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097110(2-(4-Trifluoromethyl-phenyl)-quinoline-4-carboxyli...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097083(2-(3,4-Dichloro-phenyl)-quinoline-4-carboxylic aci...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097085(2-(4-Bromo-phenyl)-6-sulfo-quinoline-4-carboxylic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097086(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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