Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50010388
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50093602(17-(1H-Imidazol-4-yl)-10,13-dimethyl-2,3,4,7,8,9,1...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50006551(CHEMBL70901 | (-)3-(4-Amino-phenyl)-3-cyclohexyl-p...)
Affinity DataIC50: 150nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094190(10,13-Dimethyl-17-(2H-pyrazol-3-yl)-2,3,4,7,8,9,10...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataIC50: 210nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409039(CHEMBL2111951)
Affinity DataIC50: 290nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50: 400nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409040(CHEMBL2111948)
Affinity DataIC50: 420nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409039(CHEMBL2111951)
Affinity DataIC50: 430nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50: 530nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataIC50: 540nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 740nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409046(CHEMBL2112782)
Affinity DataIC50: 970nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bovine)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of P450 sccMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409042(CHEMBL2112781)
Affinity DataIC50: 1.25E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094189(17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,...)
Affinity DataIC50: 1.32E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409048(CHEMBL2112772)
Affinity DataIC50: 1.52E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409040(CHEMBL2111948)
Affinity DataIC50: 1.52E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094189(17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of steroid 5-alpha-reductase type I isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094189(17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,...)
Affinity DataIC50: 1.80E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094193((R)-10,13-Dimethyl-17-thiiranyl-2,3,4,7,8,9,10,11,...)
Affinity DataIC50: 1.80E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094193((R)-10,13-Dimethyl-17-thiiranyl-2,3,4,7,8,9,10,11,...)
Affinity DataIC50: 2.50E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094201(10,13-Dimethyl-17-(3-methyl-3H-diazirin-3-yl)-2,3,...)
Affinity DataIC50: 2.50E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409044(CHEMBL2111950)
Affinity DataIC50: 2.50E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409043(CHEMBL2112775)
Affinity DataIC50: 2.50E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409045(CHEMBL2112777)
Affinity DataIC50: 2.50E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094189(17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of steroid 5-alpha-reductase type II isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409046(CHEMBL2112782)
Affinity DataIC50: 9.67E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409040(CHEMBL2111948)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of steroid 5-alpha-reductase type II isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094192(10,13-Dimethyl-17-(3-methyl-diaziridin-3-yl)-2,3,4...)
Affinity DataIC50: 1.60E+4nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094202((S)-10,13-Dimethyl-17-oxiranyl-1,2,4,7,8,9,10,11,1...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bovine)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of P450 sccMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094192(10,13-Dimethyl-17-(3-methyl-diaziridin-3-yl)-2,3,4...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409047(CHEMBL2111949)
Affinity DataIC50: 2.50E+4nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409044(CHEMBL2111950)
Affinity DataIC50: 3.20E+4nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409048(CHEMBL2112772)
Affinity DataIC50: 3.40E+4nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 6.70E+4nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409042(CHEMBL2112781)
Affinity DataIC50: 7.00E+4nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094196(17-Azetidin-2-yl-10,13-dimethyl-2,3,4,7,8,9,10,11,...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094194((S)-2-(3-Methoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,...)
Affinity DataIC50: 1.25E+5nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094193((R)-10,13-Dimethyl-17-thiiranyl-2,3,4,7,8,9,10,11,...)
Affinity DataIC50: 1.25E+5nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094201(10,13-Dimethyl-17-(3-methyl-3H-diazirin-3-yl)-2,3,...)
Affinity DataIC50: 1.25E+5nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409043(CHEMBL2112775)
Affinity DataIC50: 1.25E+5nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409045(CHEMBL2112777)
Affinity DataIC50: 3.40E+7nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409039(CHEMBL2111951)
Affinity DataKi:  3nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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