Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 50010289
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092956(A-286982 | 1-(4-acetylpiperazin-1-yl)-3-(4-(2-isop...)
Affinity DataIC50: 35nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092956(A-286982 | 1-(4-acetylpiperazin-1-yl)-3-(4-(2-isop...)
Affinity DataIC50: 44nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092953(2-{4-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-...)
Affinity DataIC50: 60nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092912(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,4-dichloro-phe...)
Affinity DataIC50: 63nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092900(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-ethyl-phenylsu...)
Affinity DataIC50: 65nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092912(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,4-dichloro-phe...)
Affinity DataIC50: 90nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092900(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-ethyl-phenylsu...)
Affinity DataIC50: 100nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092928(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dichloro-phe...)
Affinity DataIC50: 100nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092906(3-{4-[2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1...)
Affinity DataIC50: 100nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092895(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-chloro-phenyls...)
Affinity DataIC50: 110nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092916(1-(4-Acetyl-piperazin-1-yl)-3-(3-nitro-4-o-tolylsu...)
Affinity DataIC50: 120nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092943(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(2,4-dic...)
Affinity DataIC50: 140nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092936([2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-(3-morpho...)
Affinity DataIC50: 140nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092901(3-[4-(2,4-Dichloro-phenylsulfanyl)-3-nitro-phenyl]...)
Affinity DataIC50: 140nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092893(3-[3-Chloro-4-(2-morpholin-4-ylmethyl-phenylsulfan...)
Affinity DataIC50: 150nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092901(3-[4-(2,4-Dichloro-phenylsulfanyl)-3-nitro-phenyl]...)
Affinity DataIC50: 170nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092892(3-{3-Chloro-4-[2-(3-morpholin-4-yl-3-oxo-propenyl)...)
Affinity DataIC50: 180nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092917(3-{3-Chloro-4-[2-(3-morpholin-4-yl-propylamino)-ph...)
Affinity DataIC50: 180nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092892(3-{3-Chloro-4-[2-(3-morpholin-4-yl-3-oxo-propenyl)...)
Affinity DataIC50: 190nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092943(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(2,4-dic...)
Affinity DataIC50: 240nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092910(({2-[2-Chloro-4-(3-morpholin-4-yl-3-oxo-propenyl)-...)
Affinity DataIC50: 260nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092951(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-dimethylamino-...)
Affinity DataIC50: 310nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092906(3-{4-[2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1...)
Affinity DataIC50: 360nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092955(4-{2-[2-Chloro-4-(3-morpholin-4-yl-3-oxo-propenyl)...)
Affinity DataIC50: 420nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092941(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 460nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092931(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-tert-butyl-phe...)
Affinity DataIC50: 530nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092897(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 550nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092952(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 590nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092894(2-(2,4-Dichloro-phenylsulfanyl)-5-(3-morpholin-4-y...)
Affinity DataIC50: 610nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092932(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-amino-phenylsu...)
Affinity DataIC50: 620nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092902(3-[3-Bromo-4-(2,4-dichloro-phenylsulfanyl)-phenyl]...)
Affinity DataIC50: 650nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092897(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 700nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092909(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 710nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092923(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 750nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092940(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 920nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092929(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-N-(3-im...)
Affinity DataIC50: 960nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092930(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092921(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-1-morph...)
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092925(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 1.40E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092926(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-N-[3-(2...)
Affinity DataIC50: 1.60E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092913(3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenylami...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition against binding of LFA-1 to ICAM-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092939(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-N-(tetr...)
Affinity DataIC50: 2.10E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092904(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-N-(6-hy...)
Affinity DataIC50: 2.10E+3nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092949(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-N,N-bis...)
Affinity DataIC50: 2.30E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092942(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50: 2.60E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092934(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-acrylic...)
Affinity DataIC50: 2.60E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092914(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-N-(2-hy...)
Affinity DataIC50: 3.30E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092938(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-N-(2,3-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092907({3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-acrylo...)
Affinity DataIC50: 3.90E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092919(3-[3-(2,4-Dichloro-phenylsulfanyl)-phenyl]-N-[3-(2...)
Affinity DataIC50: 4.50E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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