Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with all data for entry = 50010231
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092231((4-Phenoxy-phenyl)-quinazolin-4-yl-amine | CHEMBL3...)
Affinity DataIC50: 8nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 8nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 10nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 14nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 23nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 40nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 48nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 58nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 75nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 84nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 85nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 88nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092229(7-tert-Butyl-5-(4-chloro-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 150nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 150nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM25116(cid_1400 | CHEMBL306380 | 1-tert-butyl-3-(4-methyl...)
Affinity DataIC50: 151nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM25116(cid_1400 | CHEMBL306380 | 1-tert-butyl-3-(4-methyl...)
Affinity DataIC50: 170nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092229(7-tert-Butyl-5-(4-chloro-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 220nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM25116(cid_1400 | CHEMBL306380 | 1-tert-butyl-3-(4-methyl...)
Affinity DataIC50: 250nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 270nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092226(4-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 317nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092230(7-Cyclopentyl-5-(2-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 390nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 430nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092233(7-Isopropyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 430nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 544nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 600nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 610nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092232(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM25116(cid_1400 | CHEMBL306380 | 1-tert-butyl-3-(4-methyl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092228(7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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