Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50036851
TargetD(2) dopamine receptor(Rat)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092169(N*7*,N*7*-Dipropyl-7,8-dihydro-6H-1-thia-3-aza-as-...)
Affinity DataEC50:  19nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D2L by mitogenesis assay (intri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM84637(NSC_54562 | CHEMBL240773 | QUINPIROLE | CAS_85760-...)
Affinity DataEC50:  1.70nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assay (intrin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092173(N*6*,N*6*-Dipropyl-6,7-dihydro-5H-1-thia-3-aza-s-i...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assay (intrin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM84637(NSC_54562 | CHEMBL240773 | QUINPIROLE | CAS_85760-...)
Affinity DataEC50:  2.20nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D2L by mitogenesis assay (intri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092170(N*8*,N*8*-Dipropyl-8,9-dihydro-7H-chromeno[6,5-d]t...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092169(N*7*,N*7*-Dipropyl-7,8-dihydro-6H-1-thia-3-aza-as-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assay (intrin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092170(N*8*,N*8*-Dipropyl-8,9-dihydro-7H-chromeno[6,5-d]t...)
Affinity DataEC50:  148nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D2L by mitogenesis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092173(N*6*,N*6*-Dipropyl-6,7-dihydro-5H-1-thia-3-aza-s-i...)
Affinity DataEC50:  5.70nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D2L by mitogenesis assay (intri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092169(N*7*,N*7*-Dipropyl-7,8-dihydro-6H-1-thia-3-aza-as-...)
Affinity DataIC50: 1.00E+4nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D4 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092173(N*6*,N*6*-Dipropyl-6,7-dihydro-5H-1-thia-3-aza-s-i...)
Affinity DataKi:  1.40nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D3 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092169(N*7*,N*7*-Dipropyl-7,8-dihydro-6H-1-thia-3-aza-as-...)
Affinity DataKi:  11nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D3 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092173(N*6*,N*6*-Dipropyl-6,7-dihydro-5H-1-thia-3-aza-s-i...)
Affinity DataKi:  27nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]NPA as radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092170(N*8*,N*8*-Dipropyl-8,9-dihydro-7H-chromeno[6,5-d]t...)
Affinity DataKi:  47nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]-0437 as radiolig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092173(N*6*,N*6*-Dipropyl-6,7-dihydro-5H-1-thia-3-aza-s-i...)
Affinity DataKi:  272nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D4 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092169(N*7*,N*7*-Dipropyl-7,8-dihydro-6H-1-thia-3-aza-as-...)
Affinity DataKi:  500nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]NPA as radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092170(N*8*,N*8*-Dipropyl-8,9-dihydro-7H-chromeno[6,5-d]t...)
Affinity DataKi:  510nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D3 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092172(N*7*,N*7*-Dipropyl-7,8-dihydro-6H-chromeno[8,7-d]t...)
Affinity DataKi:  536nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]-0437 as radiolig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092171(N*6*-Propyl-6,7-dihydro-5H-1-thia-3-aza-s-indacene...)
Affinity DataKi:  1.35E+3nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]NPA as radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092172(N*7*,N*7*-Dipropyl-7,8-dihydro-6H-chromeno[8,7-d]t...)
Affinity DataKi:  1.40E+3nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D3 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092171(N*6*-Propyl-6,7-dihydro-5H-1-thia-3-aza-s-indacene...)
Affinity DataKi: >3.33E+3nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D4 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092172(N*7*,N*7*-Dipropyl-7,8-dihydro-6H-chromeno[8,7-d]t...)
Affinity DataKi:  3.51E+3nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092170(N*8*,N*8*-Dipropyl-8,9-dihydro-7H-chromeno[6,5-d]t...)
Affinity DataKi:  5.92E+3nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Maastricht

Curated by ChEMBL
LigandPNGBDBM50092171(N*6*-Propyl-6,7-dihydro-5H-1-thia-3-aza-s-indacene...)
Affinity DataKi: >1.00E+4nMAssay Description:in vitro binding affinity was determined on human Dopamine receptor D3 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed