Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50036837
TargetCoagulation factor X(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50084676(2-(3'-Carbamimidoyl-biphenyl-3-yl)-5-(pyridin-4-yl...)
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: 70nMAssay Description:Inhibitory Activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50084676(2-(3'-Carbamimidoyl-biphenyl-3-yl)-5-(pyridin-4-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibitory Activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Bovine)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037996(N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  6nMAssay Description:Inhibitory Activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Bovine)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50091037(1-[5-(Diaminomethyl-amino)-2-(3-methyl-1,2,3,4-tet...)
Affinity DataKi:  19nMAssay Description:Inhibitory Activity against bovine alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL537204 | CHEMBL20...)
Affinity DataKi:  31nMAssay Description:Inhibitory Activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  150nMAssay Description:Inhibitory Activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL537204 | CHEMBL20...)
Affinity DataKi:  300nMAssay Description:Inhibitory Activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  360nMAssay Description:Inhibitory Activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTrypsin-3(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037996(N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  690nMAssay Description:Inhibitory Activity against bovine beta-trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50091037(1-[5-(Diaminomethyl-amino)-2-(3-methyl-1,2,3,4-tet...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory Activity against TrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Bovine)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037996(N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  7.90E+3nMAssay Description:Inhibitory Activity against bovine Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50091037(1-[5-(Diaminomethyl-amino)-2-(3-methyl-1,2,3,4-tet...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibitory Activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed