Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50009966
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50021548(CHEMBL35111 | (1S,3S)-1-amino-3-phosphonocyclopent...)
Affinity DataEC50:  8.60E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089518((1R,2R)-1-amino-2-(phosphonomethyl)cyclopropanecar...)
Affinity DataEC50:  7.90E+3nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089517((1R,2R)-4-Amino-cyclopentane-1,2,4-tricarboxylic a...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089105(1-Amino-3-phosphonomethylene-cyclobutanecarboxylic...)
Affinity DataEC50:  4.40E+3nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50060137((1R,2S,4s)-4-aminocyclopentane-1,2,4-tricarboxylic...)
Affinity DataEC50:  7.00E+3nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089516((1R,2S)-1-amino-2-(phosphonomethyl)cyclopropanecar...)
Affinity DataEC50:  580nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  3.90E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataEC50: >3.00E+5nMAssay Description:Agonistic activity on Human mGlu2 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50004881(Amino-(4-phosphono-phenyl)-acetic acid(RS-PPG) | (...)
Affinity DataEC50:  4.70E+3nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  500nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50021550(CHEMBL32976 | (1S,3S)-1-amino-3-phosphonocyclopent...)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataEC50:  1.70E+4nMAssay Description:Agonistic activity on Human mGlu4a receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataEC50: >3.00E+5nMAssay Description:Agonistic activity on Human Metabotropic glutamate receptor 2 expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonistic activity on Human mGlu4a receptor expressed in recombinant mammalian cells by GTPgammaS binding assay; Partial agonistMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration on Human mGlu4 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration on Human mGlu4 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration on Human mGlu2 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory concentration on Human Metabotropic glutamate receptor 2 expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed