Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50009899
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089009((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 3nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089008(Benzoic acid 4-{(S)-2-[((S)-3-acetyl-thiazolidine-...)
Affinity DataIC50: 4nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 5nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089004(2,6-Dichloro-benzoic acid 4-{(S)-2-[((S)-3-acetyl-...)
Affinity DataIC50: 6nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089006((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 9nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089001(Adamantane-1-carboxylic acid 4-{(S)-2-[((S)-3-acet...)
Affinity DataIC50: 12nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089007((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 15nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089014((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 17nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089004(2,6-Dichloro-benzoic acid 4-{(S)-2-[((S)-3-acetyl-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089003((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 25nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 34nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089006((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 35nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089012((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 40nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089009((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 60nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089002((R)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 90nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089001(Adamantane-1-carboxylic acid 4-{(S)-2-[((S)-3-acet...)
Affinity DataIC50: 140nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089014((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 150nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089008(Benzoic acid 4-{(S)-2-[((S)-3-acetyl-thiazolidine-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089007((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 170nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of alpha4-beta7 integrin mediated cell adhesionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089013((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 220nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089015((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 310nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089010((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 360nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089003((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089011((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 2.74E+3nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089002((R)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089013((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089010((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 3.53E+4nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089015((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 7.66E+4nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of alphaL-beta2 mediated cell adhesionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089011((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 2.63E+5nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 4.00E+5nMAssay Description:The antagonist activity was evaluated by alphaIlb-beta3 cell assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of alphaV-beta3 mediated cell adhesionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of alpha5-beta1 integrin mediated cell adhesionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed