Compile Data Set for Download or QSAR
Report error Found 118 Enz. Inhib. hit(s) with all data for entry = 50009710
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086986(2-[4'-(2-Benzyl-benzofuran-3-yl)-3,5-dibromo-biphe...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086896(4-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-3-bromo-bip...)
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086947(2-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-3,5-dibromo...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086950(2-{4-[4-(2-benzyl-1-benzothiophen-3-yl)phenyl]-2,6...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086972([4'-(2-Benzyl-benzo[b]thiophen-3-yl)-biphenyl-4-yl...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086911(5-[4''-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086923(4-[4'-(2-Benzyl-benzofuran-3-yl)-3-cyclopentyl-bip...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086975([4-(2-Benzyl-benzo[b]thiophen-3-yl)-5'-bromo-3''-m...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086970(4-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-biphenyl-4-...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086954([4-(2-Benzyl-benzo[b]thiophen-3-yl)-5''-bromo-4'''...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086981(4-[4''-(2-Benzyl-benzofuran-3-yl)-3-nitro-biphenyl...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086955(4-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-3,5-dibromo...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086951(4-[4'-(2-Benzyl-4,5-dimethyl-thiophen-3-yl)-biphen...)
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086902(4-[4'-(2-Benzyl-benzofuran-3-yl)-3,5-dimethyl-biph...)
Affinity DataIC50: 34nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086892(2-[4'-(2-Benzyl-benzofuran-3-yl)-3,5-dibromo-biphe...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086963(4-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxys...)
Affinity DataIC50: 39nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086973(4-[4'-(2-Benzoyl-benzofuran-3-yl)-3-cyclopentyl-bi...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086988(2-[4-(2-Benzyl-benzofuran-3-yl)-4''-methoxy-[1,1';...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086952(2-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-3,5-dibromo...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086969([4-(2-Benzyl-benzo[b]thiophen-3-yl)-5'-bromo-2'',4...)
Affinity DataIC50: 47nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086903(2-[4-(2-Benzyl-benzo[b]thiophen-3-yl)-4''-chloro-[...)
Affinity DataIC50: 52nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086916(2-[4'-(2-Benzyl-benzofuran-3-yl)-3,5-dibromo-biphe...)
Affinity DataIC50: 52nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086967([4-(2-Benzyl-benzo[b]thiophen-3-yl)-4''-ethoxy-[1,...)
Affinity DataIC50: 52nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086929(2-[4-(2-Benzyl-benzo[b]thiophen-3-yl)-4''-methoxy-...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086956(2-[4'-(2-Benzyl-benzofuran-3-yl)-3,5-dibromo-biphe...)
Affinity DataIC50: 54nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086961(N-{3-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-3,5-dibr...)
Affinity DataIC50: 54nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086957(2-[4'-(2-Benzyl-benzofuran-3-yl)-3-cyclopentyl-bip...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086953(2-[4'-(2-Benzyl-benzofuran-3-yl)-3-bromo-biphenyl-...)
Affinity DataIC50: 56nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086994(2-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-3-bromo-bip...)
Affinity DataIC50: 58nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086905([4-(2-Benzyl-benzo[b]thiophen-3-yl)-2'',3''-dimeth...)
Affinity DataIC50: 71nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086914(2-[4'-(2-Benzyl-benzofuran-3-yl)-3,5-dimethyl-biph...)
Affinity DataIC50: 74nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086993(4-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxys...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086906(2-{4'-[2-(2,2-Dimethyl-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50: 77nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086985(2-{4'-[2-(4-Methoxy-benzyl)-benzo[b]thiophen-3-yl]...)
Affinity DataIC50: 77nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086938([4-(2-Benzyl-benzo[b]thiophen-3-yl)-4''-methoxy-[1...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086932([4'-(2-Benzyl-benzofuran-3-yl)-4-phenethyloxy-biph...)
Affinity DataIC50: 82nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086977(2-{4'-[2-(2,4-Dimethoxy-benzyl)-benzo[b]thiophen-3...)
Affinity DataIC50: 85nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086989(2-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-biphenyl-4-...)
Affinity DataIC50: 95nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086897([4-(2-Benzyl-benzo[b]thiophen-3-yl)-[1,1':3',1'']t...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086901([4-(2-Benzyl-benzo[b]thiophen-3-yl)-3'',4'',5''-tr...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086965(2-(4'-(2-benzylbenzo[b]thiophen-3-yl)-3,5-dibromob...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086941(3-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxys...)
Affinity DataIC50: 106nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086931(2-{4'-[2-(Hydroxy-phenyl-methyl)-benzofuran-3-yl]-...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086974([4'-(2-Butyl-benzo[b]thiophen-3-yl)-biphenyl-4-ylo...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086939(2-{4'-[2-(3,4-Dimethoxy-benzyl)-benzo[b]thiophen-3...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086946(2-{4'-[2-(4-Fluoro-benzyl)-benzo[b]thiophen-3-yl]-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086995(2-{4'-[2-(2,4-Dihydroxy-benzyl)-benzo[b]thiophen-3...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086919(2-[4'-(2-Benzyl-benzofuran-3-yl)-3,5-dibromo-biphe...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086927(2-{3,5-Dibromo-4''-[5-methyl-2-(4-trifluoromethyl-...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086930(2-[4'-(2-Benzyl-5-fluoro-benzofuran-3-yl)-biphenyl...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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