Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50048485
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 5nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217563(CHEMBL125671)
Affinity DataIC50: 330nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217559(CHEMBL123266)
Affinity DataIC50: 410nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217545(CHEMBL341304)
Affinity DataIC50: 630nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217561(CHEMBL340860)
Affinity DataIC50: 650nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217546(CHEMBL125123)
Affinity DataIC50: 710nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217553(CHEMBL339749)
Affinity DataIC50: 760nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217551(CHEMBL419791)
Affinity DataIC50: 760nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217558(CHEMBL338684)
Affinity DataIC50: 960nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217546(CHEMBL125123)
Affinity DataIC50: 1.09E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217550(CI-1018 | CHEMBL111925)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217557(CHEMBL123782)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217555(CHEMBL332854)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217560(CHEMBL126581)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217549(CHEMBL332853)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217545(CHEMBL341304)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217552(CHEMBL339408)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217560(CHEMBL126581)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217553(CHEMBL339749)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217549(CHEMBL332853)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217552(CHEMBL339408)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]rolipram from rat brain membrane suspensionsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217558(CHEMBL338684)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217551(CHEMBL419791)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217555(CHEMBL332854)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217556(CHEMBL125828)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217550(CI-1018 | CHEMBL111925)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217559(CHEMBL123266)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217562(CHEMBL420335)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217556(CHEMBL125828)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217558(CHEMBL338684)
Affinity DataIC50: 7.85E+3nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217563(CHEMBL125671)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217551(CHEMBL419791)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217555(CHEMBL332854)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
LigandPNGBDBM50217549(CHEMBL332853)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217557(CHEMBL123782)
Affinity DataIC50: 4.37E+4nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217549(CHEMBL332853)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
LigandPNGBDBM50217560(CHEMBL126581)
Affinity DataIC50: 6.53E+4nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
LigandPNGBDBM50217553(CHEMBL339749)
Affinity DataIC50: 7.17E+4nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217560(CHEMBL126581)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217550(CI-1018 | CHEMBL111925)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
LigandPNGBDBM50217552(CHEMBL339408)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217561(CHEMBL340860)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217553(CHEMBL339749)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
LigandPNGBDBM50217547(CHEMBL338657)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
LigandPNGBDBM50217546(CHEMBL125123)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217547(CHEMBL338657)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
LigandPNGBDBM50217555(CHEMBL332854)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
LigandPNGBDBM50217561(CHEMBL340860)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217562(CHEMBL420335)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Institut De Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217548(CHEMBL333585)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2018
Entry Details Article
PubMed
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