Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50009348
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082395((3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 3nMAssay Description:Binding affinity against dopamine transporter (DAT) was evaluated using competitive binding assay and [3H]mazindol as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | piperidine based analogue of cocain...)
Affinity DataKi:  43nMAssay Description:Binding affinity against dopamine transporter (DAT) was evaluated using competitive binding assay and [3H]mazindol as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | piperidine based analogue of cocain...)
Affinity DataKi:  43nMAssay Description:Binding affinity against dopamine transporter (DAT) was evaluated using competitive binding assay and [3H]mazindol as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082393(piperidine based analogue of cocaine | CHEMBL44107...)
Affinity DataKi:  96nMAssay Description:Binding affinity against dopamine transporter (DAT) was evaluated using competitive binding assay and [3H]mazindol as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | piperidine based analogue of cocain...)
Affinity DataKi:  110nMAssay Description:Inhibition of monoamine [3H]DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | piperidine based analogue of cocain...)
Affinity DataKi:  112nMAssay Description:Inhibition of monoamine [3H]DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082393(piperidine based analogue of cocaine | CHEMBL44107...)
Affinity DataKi:  193nMAssay Description:Inhibition of monoamine [3H]DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082393(piperidine based analogue of cocaine | CHEMBL44107...)
Affinity DataKi:  231nMAssay Description:Norepinephrine transporter activity was determined by inhibition of monoamine [3H]-NE reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082393(piperidine based analogue of cocaine | CHEMBL44107...)
Affinity DataKi:  243nMAssay Description:Inhibition of monoamine [3H]5-HT reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | piperidine based analogue of cocain...)
Affinity DataKi:  888nMAssay Description:Inhibition of monoamine [3H]5-HT reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | piperidine based analogue of cocain...)
Affinity DataKi:  888nMAssay Description:Inhibition of monoamine [3H]5-HT reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | piperidine based analogue of cocain...)
Affinity DataKi:  2.03E+3nMAssay Description:Norepinephrine transporter activity was determined by inhibition of monoamine [3H]-NE reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | piperidine based analogue of cocain...)
Affinity DataKi:  2.03E+3nMAssay Description:Norepinephrine transporter activity was determined by inhibition of monoamine [3H]-NE reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed