Compile Data Set for Download or QSAR
Report error Found 145 Enz. Inhib. hit(s) with all data for entry = 687
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5106(4-[(2S)-2-{[(1S)-2-hydroxy-1-[3-(naphthalen-2-ylme...)
Affinity DataIC50: 1.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5099(4-[(2S)-2-acetamido-2-{[(1S)-2-hydroxy-1-[3-(napht...)
Affinity DataIC50: 2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5103(4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]...)
Affinity DataIC50: 2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5105(4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]...)
Affinity DataIC50: 2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5074(4-[(2S)-2-{[(1S)-1-{3-[(3-chloro-4-iodophenyl)meth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5075(4-[(2S)-2-{[(1S)-1-{3-[(3-bromo-4-iodophenyl)methy...)
Affinity DataIC50: 3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5086(4-[(2S)-2-(1-phenylacetamido)-2-{[(1S)-1-(3-{[4-(t...)
Affinity DataIC50: 3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5090(4-[(2S)-2-[1-(naphthalen-2-yl)acetamido]-2-{[(1S)-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5102(4-[(2S)-2-acetamido-2-{[(1S)-1-[3-(naphthalen-2-yl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5104(4-[(2S)-2-{[(1S)-2-hydroxy-1-(3-{[4-(trifluorometh...)
Affinity DataIC50: 3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5072(4-[(2S)-2-{[(1S)-1-{3-[(3,4-dibromophenyl)methyl]-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5085(4-[(2S)-2-acetamido-2-{[(1S)-2-hydroxy-1-{3-[(4-io...)
Affinity DataIC50: 4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5098(4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]...)
Affinity DataIC50: 4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5100(4-[(2S)-2-acetamido-2-{[(1S)-2-hydroxy-1-(3-{[4-(t...)
Affinity DataIC50: 4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5071(4-[(2S)-2-acetamido-2-{[(1S)-1-{3-[(4-iodophenyl)m...)
Affinity DataIC50: 5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5073(4-[(2S)-2-{[(1S)-1-{3-[(3-bromo-4-chlorophenyl)met...)
Affinity DataIC50: 5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5087(4-[(2S)-2-[1-(thiophen-2-yl)acetamido]-2-{[(1S)-1-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5091(4-[(2S)-2-[1-(1H-indol-3-yl)acetamido]-2-{[(1S)-1-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5096(4-[(2S)-2-acetamido-2-{[(1S)-1-[3-(naphthalen-2-yl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5101(4-[(2S)-2-acetamido-2-{[(1S)-3-phenyl-1-(3-{[4-(tr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5088(4-[(2S)-2-[1-(3,4-difluorophenyl)acetamido]-2-{[(1...)
Affinity DataIC50: 6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5089(4-[(2S)-2-[1-(4-methoxyphenyl)acetamido]-2-{[(1S)-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5095(4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]...)
Affinity DataIC50: 6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5069(4-[(2S)-2-{[(1S)-1-{3-[(4-bromophenyl)methyl]-1,2,...)
Affinity DataIC50: 7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5084(4-[(2S)-2-{[(1S)-1-{3-[(4-bromophenyl)methyl]-1,2,...)
Affinity DataIC50: 7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5097(CHEMBL103838 | 4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{...)
Affinity DataIC50: 7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5094(4-[(2S)-2-{[(1S)-3-carbamoyl-1-[3-(naphthalen-2-yl...)
Affinity DataIC50: 8.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5082(4-[(2S)-2-{[(1S)-1-{3-[(4-chlorophenyl)methyl]-1,2...)
Affinity DataIC50: 1.10E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5066(4-[(2S)-2-{[(1S)-1-{3-[(4-chlorophenyl)methyl]-1,2...)
Affinity DataIC50: 1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5081(4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{[4-(trifluorome...)
Affinity DataIC50: 1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5093(4-[(2S)-2-{[(1S)-3-carbamoyl-1-{3-[(3,4-dichloroph...)
Affinity DataIC50: 1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5071(4-[(2S)-2-acetamido-2-{[(1S)-1-{3-[(4-iodophenyl)m...)
Affinity DataIC50: 1.80E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5059(4-[(2S)-2-{[(1S)-3-carbamoyl-1-{3-[(4-chlorophenyl...)
Affinity DataIC50: 2.60E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5069(4-[(2S)-2-{[(1S)-1-{3-[(4-bromophenyl)methyl]-1,2,...)
Affinity DataIC50: 3.10E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5083(4-[(2S)-2-acetamido-2-{[(1S)-1-{3-[(4-fluorophenyl...)
Affinity DataIC50: 3.10E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5080(4-[(2S)-2-acetamido-2-{[(1S)-2-(1H-indol-3-yl)-1-(...)
Affinity DataIC50: 3.20E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5084(4-[(2S)-2-{[(1S)-1-{3-[(4-bromophenyl)methyl]-1,2,...)
Affinity DataIC50: 3.20E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5065(4-[(2S)-2-acetamido-2-{[(1S)-1-{3-[(4-methylphenyl...)
Affinity DataIC50: 3.30E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5105(4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]...)
Affinity DataIC50: 3.50E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5058(4-[(2S)-2-{[(1S)-3-carbamoyl-1-(3-{[4-(propan-2-yl...)
Affinity DataIC50: 3.60E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5085(4-[(2S)-2-acetamido-2-{[(1S)-2-hydroxy-1-{3-[(4-io...)
Affinity DataIC50: 3.70E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5072(4-[(2S)-2-{[(1S)-1-{3-[(3,4-dibromophenyl)methyl]-...)
Affinity DataIC50: 3.90E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5075(4-[(2S)-2-{[(1S)-1-{3-[(3-bromo-4-iodophenyl)methy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5079(4-[(2S)-2-{[(1S)-2-carbamoyl-1-(3-{[4-(trifluorome...)
Affinity DataIC50: 4.30E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5073(4-[(2S)-2-{[(1S)-1-{3-[(3-bromo-4-chlorophenyl)met...)
Affinity DataIC50: 4.50E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5090(4-[(2S)-2-[1-(naphthalen-2-yl)acetamido]-2-{[(1S)-...)
Affinity DataIC50: 4.90E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5074(4-[(2S)-2-{[(1S)-1-{3-[(3-chloro-4-iodophenyl)meth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5063(CHEMBL310313 | 4-[(2S)-2-{[(1S)-3-carbamoyl-1-[3-(...)
Affinity DataIC50: 5.50E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5103(4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]...)
Affinity DataIC50: 6.00E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5091(4-[(2S)-2-[1-(1H-indol-3-yl)acetamido]-2-{[(1S)-1-...)
Affinity DataIC50: 6.20E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
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