Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 1679
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13304(4-hydroxy-3-{[(3S)-2-oxo-3-{[5-(pyridin-3-yl)thiop...)
Affinity DataKi:  2nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13306(4-hydroxy-3-{[(3S)-3-{[5-(1,2-oxazol-3-yl)thiophen...)
Affinity DataKi:  3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13286(4-hydroxy-3-{[(3S)-3-[(7-methoxynaphthalene-2-)sul...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13283(4-amino-3-{[(3S)-3-[(7-methoxynaphthalene-2-)(meth...)
Affinity DataKi:  4nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13281(4-amino-3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfo...)
Affinity DataKi:  6nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13303(4-amino-3-{[(3S)-2-oxo-3-{[5-(pyridin-3-yl)thiophe...)
Affinity DataKi:  6nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13279(4-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)
Affinity DataKi:  6.90nM ΔG°:  -46.1kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13305(4-Amino-3-[3-(S)-(5-isoxazol-3-ylthiophene-2-ylsul...)
Affinity DataKi:  7nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13288(methyl 2-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxyna...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13288(methyl 2-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxyna...)
Affinity DataKi:  12nM ΔG°:  -44.8kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13282(3-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)
Affinity DataKi:  22nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13298(3-[2-Oxo-3-(S)-(5-pyridin-3-ylthiophene-2-ylsulfon...)
Affinity DataKi:  41nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13280(3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-...)
Affinity DataKi:  47nM ΔG°:  -41.4kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13301(3-[3-(S)-(5-Isoxazol-3-ylthiophene-2-ylsulfonylami...)
Affinity DataKi:  49nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13299(3-{[(3S)-2-oxo-3-{[5-(pyridin-4-yl)thiophene-2-]su...)
Affinity DataKi:  55nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13293(3-{[(3S)-2-oxo-3-{[4-(pyridin-4-yl)benzene]sulfona...)
Affinity DataKi:  130nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13302(4-fluoro-3-[((3S)-2-oxo-3-{[(5-pyridin-3-ylthien-2...)
Affinity DataKi:  130nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13297(3-{[(3S)-2-oxo-3-{[5-(pyridin-2-yl)thiophene-2-]su...)
Affinity DataKi:  140nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13300(3-{[(3S)-3-{[5-(2-methoxypyrimidin-4-yl)thiophene-...)
Affinity DataKi:  150nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13291(3-{[(3S)-2-oxo-3-{[4-(pyridin-2-yl)benzene]sulfona...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13290(3-{[(3S)-2-oxo-3-[(4-phenylbenzene)sulfonamido]pyr...)
Affinity DataKi:  160nM ΔG°:  -38.4kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13283(4-amino-3-{[(3S)-3-[(7-methoxynaphthalene-2-)(meth...)
Affinity DataKi:  189nM ΔG°:  -38.0kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13292(3-{[(3S)-2-oxo-3-{[4-(pyridin-3-yl)benzene]sulfona...)
Affinity DataKi:  210nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13281(4-amino-3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfo...)
Affinity DataKi:  299nM ΔG°:  -36.9kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13286(4-hydroxy-3-{[(3S)-3-[(7-methoxynaphthalene-2-)sul...)
Affinity DataKi:  305nM ΔG°:  -36.8kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13295(4-(4-{[(3S)-1-[(3-carbamimidoylphenyl)methyl]-2-ox...)
Affinity DataKi:  330nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13282(3-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)
Affinity DataKi:  704nM ΔG°:  -34.8kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13280(3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-...)
Affinity DataKi:  853nM ΔG°:  -34.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13284(N-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxynaphthale...)
Affinity DataKi:  919nM ΔG°:  -34.1kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13287(2-hydroxy-5-{[(3S)-3-[(7-methoxynaphthalene-2-)sul...)
Affinity DataKi:  983nM ΔG°:  -33.9kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13294(4-(4-{[(3S)-1-[(3-carbamimidoylphenyl)methyl]-2-ox...)
Affinity DataKi: >1.00E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13285(3-Amino-5-[3-(S)-(7-methoxynaphthalen-2-ylsulfonyl...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13289(2-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxynaphthale...)
Affinity DataKi:  1.30E+3nM ΔG°:  -33.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13303(4-amino-3-{[(3S)-2-oxo-3-{[5-(pyridin-3-yl)thiophe...)
Affinity DataKi:  1.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13305(4-Amino-3-[3-(S)-(5-isoxazol-3-ylthiophene-2-ylsul...)
Affinity DataKi:  1.70E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13301(3-[3-(S)-(5-Isoxazol-3-ylthiophene-2-ylsulfonylami...)
Affinity DataKi:  1.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13297(3-{[(3S)-2-oxo-3-{[5-(pyridin-2-yl)thiophene-2-]su...)
Affinity DataKi:  2.10E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13296(3-{[(3S)-3-{[4-(1-methyl-1H-imidazol-2-yl)benzene]...)
Affinity DataKi:  2.60E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13295(4-(4-{[(3S)-1-[(3-carbamimidoylphenyl)methyl]-2-ox...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13306(4-hydroxy-3-{[(3S)-3-{[5-(1,2-oxazol-3-yl)thiophen...)
Affinity DataKi:  2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13304(4-hydroxy-3-{[(3S)-2-oxo-3-{[5-(pyridin-3-yl)thiop...)
Affinity DataKi:  2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13302(4-fluoro-3-[((3S)-2-oxo-3-{[(5-pyridin-3-ylthien-2...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13300(3-{[(3S)-3-{[5-(2-methoxypyrimidin-4-yl)thiophene-...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13299(3-{[(3S)-2-oxo-3-{[5-(pyridin-4-yl)thiophene-2-]su...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13298(3-[2-Oxo-3-(S)-(5-pyridin-3-ylthiophene-2-ylsulfon...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13296(3-{[(3S)-3-{[4-(1-methyl-1H-imidazol-2-yl)benzene]...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13294(4-(4-{[(3S)-1-[(3-carbamimidoylphenyl)methyl]-2-ox...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13293(3-{[(3S)-2-oxo-3-{[4-(pyridin-4-yl)benzene]sulfona...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13292(3-{[(3S)-2-oxo-3-{[4-(pyridin-3-yl)benzene]sulfona...)
Affinity DataKi: >2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13284(N-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxynaphthale...)
Affinity DataKi: >2.90E+3nM ΔG°: >-31.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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