Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50036744
LigandPNGBDBM50079974((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-1-ylmet...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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LigandPNGBDBM50079961((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-2-ylmet...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50369443(CHEMBL252953)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079956((S)-2-[2-({(S)-2-[2-(3-Benzyl-3H-imidazol-4-yl)-ac...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079966((S)-2-{2-[((S)-3-Methyl-2-{2-[3-(4-nitro-benzyl)-3...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079978((S)-2-{2-[((S)-2-{2-[3-((E)-3,7-Dimethyl-octa-2,6-...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079971((S)-2-{2-[((S)-2-{2-[3-(4-Fluoro-benzyl)-3H-imidaz...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079968((S)-2-{2-[((S)-2-{2-[3-(4-Methoxy-benzyl)-3H-imida...)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079962((S)-2-[2-({(S)-3-Methyl-2-[2-(3-pyridin-4-ylmethyl...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079963((S)-4-Methylsulfanyl-2-{2-[((S)-3-methyl-2-{2-[3-(...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079964((S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethy...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079965((S)-2-{2-[((S)-3-Methyl-2-{2-[1-(4-nitro-benzyl)-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079975((S)-2-{2-[((S)-2-{2-[3-(4-Cyano-benzyl)-3H-imidazo...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50369443(CHEMBL252953)
Affinity DataIC50: 67nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079976((S)-2-[2-({(S)-3-Methyl-2-[2-(1-pyridin-4-ylmethyl...)
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079979((S)-2-[2-({(S)-2-[2-(1-Benzyl-1H-imidazol-4-yl)-ac...)
Affinity DataIC50: 82nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079966((S)-2-{2-[((S)-3-Methyl-2-{2-[3-(4-nitro-benzyl)-3...)
Affinity DataIC50: 92nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079968((S)-2-{2-[((S)-2-{2-[3-(4-Methoxy-benzyl)-3H-imida...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079971((S)-2-{2-[((S)-2-{2-[3-(4-Fluoro-benzyl)-3H-imidaz...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079956((S)-2-[2-({(S)-2-[2-(3-Benzyl-3H-imidazol-4-yl)-ac...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079963((S)-4-Methylsulfanyl-2-{2-[((S)-3-methyl-2-{2-[3-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079974((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-1-ylmet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079978((S)-2-{2-[((S)-2-{2-[3-((E)-3,7-Dimethyl-octa-2,6-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079961((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-2-ylmet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079964((S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethy...)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed