Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50009044
LigandPNGBDBM50079667((S)-2-[3-({(4-Cyano-benzyl)-[3-(4-cyano-benzyl)-3H...)
Affinity DataIC50: 0.410nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079661((S)-2-[3-({(4-Cyano-benzyl)-[3-(4-cyano-benzyl)-3H...)
Affinity DataIC50: 5nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079664((S)-2-(3-{[(4-Cyano-benzyl)-(3H-imidazol-4-ylmethy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant Ha-Ras by bovine brain farnesyltransferaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50079674((S)-2-[3-({Butyl-[3-(4-cyano-benzyl)-3H-imidazol-4...)
Affinity DataIC50: 14nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079666((S)-2-[3-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmet...)
Affinity DataIC50: 23nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079675((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-(4-nitro-benzy...)
Affinity DataIC50: 27nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079663((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-naphthalen-2-y...)
Affinity DataIC50: 55nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079660((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-naphthalen-1-y...)
Affinity DataIC50: 58nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079678((S)-2-[3-({Butyl-[3-(4-cyano-benzyl)-3H-imidazol-4...)
Affinity DataIC50: 183nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079676((S)-2-(3-{[Benzyl-(1H-imidazol-4-ylmethyl)-amino]-...)
Affinity DataIC50: 255nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079677((S)-2-[3-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmet...)
Affinity DataIC50: 260nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079673((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-phenethyl-amin...)
Affinity DataIC50: 300nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079672((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-(4-methoxy-ben...)
Affinity DataIC50: 355nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079671((S)-2-(3-{[Bis-(1H-imidazol-4-ylmethyl)-amino]-met...)
Affinity DataIC50: 870nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant Ha-Ras by bovine brain farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079670((S)-2-(3-{[(4-Cyano-benzyl)-(3H-imidazol-4-ylmethy...)
Affinity DataIC50: 1.08E+3nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079668((S)-2-(3-{[Bis-(4-nitro-benzyl)-amino]-methyl}-ben...)
Affinity DataIC50: 1.60E+3nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079659((S)-2-(3-{[Benzoyl-(1H-imidazol-4-ylmethyl)-amino]...)
Affinity DataIC50: 1.75E+3nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079664((S)-2-(3-{[(4-Cyano-benzyl)-(3H-imidazol-4-ylmethy...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of geranylgeranyl transferase I (GGTase-I)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079669((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-methyl-amino]-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079671((S)-2-(3-{[Bis-(1H-imidazol-4-ylmethyl)-amino]-met...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of geranylgeranyl transferase I (GGTase-I)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079665((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50: 5.76E+4nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079662((S)-4-Methylsulfanyl-2-{3-[(4-nitro-benzylamino)-m...)
Affinity DataIC50: 8.00E+4nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed