Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50008989
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50039604((-)-1''-(3-Iodo-benzyl)-4-phenyl-[1,3'']bipiperidi...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079277(trans-trans-1-(3-iodobenzyl)-7-(4-phenylpiperidin-...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079275([(4aR,6R,7R,8aR)-6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079278((4aR,6R,7R,8aR)-1-((E)-3-Iodo-allyl)-7-(4-phenyl-p...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079276((4aR,6R,7R,8aR)-7-(4-Phenyl-piperidin-1-yl)-decahy...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079274(trans-trans-1-(4-fluorobenzyl)-7-(4-phenylpiperidi...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50018094((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079280((4aR,6R,7R,8aR)-1-(3-Iodo-benzyl)-6-(4-phenyl-pipe...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079279((4aR,6R,7R,8aR)-1-(4-Fluoro-benzyl)-6-(4-phenyl-pi...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079274(trans-trans-1-(4-fluorobenzyl)-7-(4-phenylpiperidi...)
Affinity DataKi:  21nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50018094((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...)
Affinity DataKi:  26nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50018094((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...)
Affinity DataKi:  34nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50039604((-)-1''-(3-Iodo-benzyl)-4-phenyl-[1,3'']bipiperidi...)
Affinity DataKi:  92nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079275([(4aR,6R,7R,8aR)-6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataKi:  110nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079275([(4aR,6R,7R,8aR)-6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataKi:  110nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079278((4aR,6R,7R,8aR)-1-((E)-3-Iodo-allyl)-7-(4-phenyl-p...)
Affinity DataKi:  125nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079274(trans-trans-1-(4-fluorobenzyl)-7-(4-phenylpiperidi...)
Affinity DataKi:  127nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50039604((-)-1''-(3-Iodo-benzyl)-4-phenyl-[1,3'']bipiperidi...)
Affinity DataKi:  190nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079275([(4aR,6R,7R,8aR)-6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataKi:  233nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079275([(4aR,6R,7R,8aR)-6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataKi:  233nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079278((4aR,6R,7R,8aR)-1-((E)-3-Iodo-allyl)-7-(4-phenyl-p...)
Affinity DataKi:  363nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079276((4aR,6R,7R,8aR)-7-(4-Phenyl-piperidin-1-yl)-decahy...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079276((4aR,6R,7R,8aR)-7-(4-Phenyl-piperidin-1-yl)-decahy...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079276((4aR,6R,7R,8aR)-7-(4-Phenyl-piperidin-1-yl)-decahy...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079276((4aR,6R,7R,8aR)-7-(4-Phenyl-piperidin-1-yl)-decahy...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50046961(CHEMBL94733 | CHEMBL1204310 | (3'R,4'R)-4-Phenyl-[...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed