Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50008831
Target5-hydroxytryptamine receptor 1A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077661(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  2.60nMAssay Description:In vitro binding affinity against 5-HT1A receptor of rat hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077658(1,1-Dioxo-2-[4-(3-phenyl-pyrrolidin-1-yl)-butyl]-1...)
Affinity DataKi:  2.70nMAssay Description:In vitro binding affinity against 5-HT1A receptor of rat hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077664(2-{4-[3-(4-Fluoro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  4.20nMAssay Description:In vitro binding affinity against 5-HT1A receptor of rat hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50077662(2-[4-(3-Phenyl-pyrrolidin-1-yl)-butyl]-2,3-dihydro...)
Affinity DataKi:  11nMAssay Description:In vitro binding affinity against Alpha-2 adrenergic receptor of rat cerebral cortex using [3H]RX-821002More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50077660(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity against Alpha-2 adrenergic receptor of rat cerebral cortex using [3H]RX-821002More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077662(2-[4-(3-Phenyl-pyrrolidin-1-yl)-butyl]-2,3-dihydro...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity against 5-HT1A receptor of rat hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077663({3-[3-(4-Chloro-phenyl)-pyrrolidin-1-ylmethyl]-phe...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity against 5-HT1A receptor of rat hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50077658(1,1-Dioxo-2-[4-(3-phenyl-pyrrolidin-1-yl)-butyl]-1...)
Affinity DataKi:  16nMAssay Description:In vitro binding affinity against Alpha-2 adrenergic receptor of rat cerebral cortex using [3H]RX-821002More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50077659([3-(3-Phenyl-pyrrolidin-1-ylmethyl)-phenyl]-piperi...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity against Alpha-2 adrenergic receptor of rat cerebral cortex using [3H]RX-821002More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077660(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  30nMAssay Description:In vitro binding affinity against 5-HT1A receptor of rat hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077659([3-(3-Phenyl-pyrrolidin-1-ylmethyl)-phenyl]-piperi...)
Affinity DataKi:  31nMAssay Description:In vitro binding affinity against 5-HT1A receptor of rat hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077658(1,1-Dioxo-2-[4-(3-phenyl-pyrrolidin-1-yl)-butyl]-1...)
Affinity DataKi:  34nMAssay Description:In vitro binding affinity against 5-HT2A receptor of rat cerebral cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50077663({3-[3-(4-Chloro-phenyl)-pyrrolidin-1-ylmethyl]-phe...)
Affinity DataKi:  44nMAssay Description:In vitro binding affinity against Alpha-2 adrenergic receptor of rat cerebral cortex using [3H]RX-821002More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077662(2-[4-(3-Phenyl-pyrrolidin-1-yl)-butyl]-2,3-dihydro...)
Affinity DataKi:  46nMAssay Description:In vitro binding affinity against 5-HT2A receptor of rat cerebral cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077663({3-[3-(4-Chloro-phenyl)-pyrrolidin-1-ylmethyl]-phe...)
Affinity DataKi:  46nMAssay Description:In vitro binding affinity against 5-HT2A receptor of rat cerebral cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50077661(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  56nMAssay Description:In vitro binding affinity against Alpha-2 adrenergic receptor of rat cerebral cortex using [3H]RX-821002More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077662(2-[4-(3-Phenyl-pyrrolidin-1-yl)-butyl]-2,3-dihydro...)
Affinity DataKi:  77nMAssay Description:In vitro binding affinity against Dopamine receptor D2 of rat striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077660(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  184nMAssay Description:In vitro binding affinity against 5-HT2A receptor of rat cerebral cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077660(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  185nMAssay Description:In vitro binding affinity against Dopamine receptor D2 of rat striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077658(1,1-Dioxo-2-[4-(3-phenyl-pyrrolidin-1-yl)-butyl]-1...)
Affinity DataKi:  195nMAssay Description:In vitro binding affinity against Dopamine receptor D2 of rat striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077661(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  232nMAssay Description:In vitro binding affinity against 5-HT2A receptor of rat cerebral cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077664(2-{4-[3-(4-Fluoro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  263nMAssay Description:In vitro binding affinity against Dopamine receptor D2 of rat striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077659([3-(3-Phenyl-pyrrolidin-1-ylmethyl)-phenyl]-piperi...)
Affinity DataKi:  320nMAssay Description:In vitro binding affinity against 5-HT2A receptor of rat cerebral cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077661(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  327nMAssay Description:In vitro binding affinity against Dopamine receptor D2 of rat striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077663({3-[3-(4-Chloro-phenyl)-pyrrolidin-1-ylmethyl]-phe...)
Affinity DataKi:  334nMAssay Description:In vitro binding affinity against Dopamine receptor D2 of rat striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50077664(2-{4-[3-(4-Fluoro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  334nMAssay Description:In vitro binding affinity against Alpha-2 adrenergic receptor of rat cerebral cortex using [3H]RX-821002More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077664(2-{4-[3-(4-Fluoro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi: >367nMAssay Description:In vitro binding affinity against 5-HT2A receptor of rat cerebral cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077659([3-(3-Phenyl-pyrrolidin-1-ylmethyl)-phenyl]-piperi...)
Affinity DataKi:  783nMAssay Description:In vitro binding affinity against Dopamine receptor D2 of rat striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077661(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  1.57E+3nMAssay Description:In vitro binding affinity against Dopamine receptor D1 of rat striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077660(2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  1.62E+3nMAssay Description:In vitro binding affinity against Dopamine receptor D1 of rat striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077662(2-[4-(3-Phenyl-pyrrolidin-1-yl)-butyl]-2,3-dihydro...)
Affinity DataKi:  1.95E+3nMAssay Description:In vitro binding affinity against Dopamine receptor D1 of rat striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077664(2-{4-[3-(4-Fluoro-phenyl)-pyrrolidin-1-yl]-butyl}-...)
Affinity DataKi:  6.67E+3nMAssay Description:In vitro binding affinity against Dopamine receptor D1 of rat striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077658(1,1-Dioxo-2-[4-(3-phenyl-pyrrolidin-1-yl)-butyl]-1...)
Affinity DataKi:  1.25E+4nMAssay Description:In vitro binding affinity against Dopamine receptor D1 of rat striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077663({3-[3-(4-Chloro-phenyl)-pyrrolidin-1-ylmethyl]-phe...)
Affinity DataKi:  3.76E+4nMAssay Description:In vitro binding affinity against Dopamine receptor D1 of rat striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Postech

Curated by ChEMBL
LigandPNGBDBM50077659([3-(3-Phenyl-pyrrolidin-1-ylmethyl)-phenyl]-piperi...)
Affinity DataKi:  8.81E+4nMAssay Description:In vitro binding affinity against Dopamine receptor D1 of rat striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed