Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50008735
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076678((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50403733(CL-191121 | CHEMBL1206880)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-tri...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076671((4R,6S)-3-{(2R,3R)-2-[((S)-1-Carboxy-2-methyl-prop...)
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076671((4R,6S)-3-{(2R,3R)-2-[((S)-1-Carboxy-2-methyl-prop...)
Affinity DataIC50: 91nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076673(Sodium; (2S,5R,6R)-6-((S)-1-hydroxy-ethyl)-3,3-dim...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50403733(CL-191121 | CHEMBL1206880)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076678((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954(UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076674(Sodium; (2S,5R,6S)-6-((S)-1-hydroxy-ethyl)-3,3-dim...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076672((2S,5R,6S)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076672((2S,5R,6S)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076677(Sodium; (2S,5R,6S)-6-((R)-1-hydroxy-ethyl)-3,3-dim...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076675(Sodium; (2S,5R,6R)-6-hydroxymethyl-3,3-dimethyl-7-...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-tri...)
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076677(Sodium; (2S,5R,6S)-6-((R)-1-hydroxy-ethyl)-3,3-dim...)
Affinity DataIC50: 4.79E+4nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076676(Sodium; (2S,5R,6S)-6-hydroxymethyl-3,3-dimethyl-7-...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076675(Sodium; (2S,5R,6R)-6-hydroxymethyl-3,3-dimethyl-7-...)
Affinity DataIC50: 6.59E+4nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954(UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...)
Affinity DataIC50: 6.59E+4nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076673(Sodium; (2S,5R,6R)-6-((S)-1-hydroxy-ethyl)-3,3-dim...)
Affinity DataIC50: 2.04E+5nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076676(Sodium; (2S,5R,6S)-6-hydroxymethyl-3,3-dimethyl-7-...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibitory activity against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076674(Sodium; (2S,5R,6S)-6-((S)-1-hydroxy-ethyl)-3,3-dim...)
Affinity DataIC50: 3.34E+5nMAssay Description:Inhibitory activity against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed