Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50008691
LigandPNGBDBM50076142((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)
Affinity DataIC50: 7.30nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076142((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076127((S)-2-{[5-(2-Imidazol-1-yl-ethoxy)-biphenyl-2-carb...)
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076135((2S)-2-(4-((1H-imidazol-4-yl)methylamino)-2-(napht...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076130((S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076141(2-[4-((R)-2-Amino-3-mercapto-propylamino)-2-naphth...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076126((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076133((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-3',5'-d...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076128((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)
Affinity DataIC50: 183nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076141(2-[4-((R)-2-Amino-3-mercapto-propylamino)-2-naphth...)
Affinity DataIC50: 203nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076131((S)-2-{4-[(1H-Imidazol-2-ylmethyl)-amino]-2-naphth...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076128((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)
Affinity DataIC50: 240nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076127((S)-2-{[5-(2-Imidazol-1-yl-ethoxy)-biphenyl-2-carb...)
Affinity DataIC50: 303nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076132((S)-4-Methyl-2-({4-[(pyridin-4-ylmethyl)-amino]-bi...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076133((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-3',5'-d...)
Affinity DataIC50: 900nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076126((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076145((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-4-yl...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076136((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-2-yl...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076135((2S)-2-(4-((1H-imidazol-4-yl)methylamino)-2-(napht...)
Affinity DataIC50: 5.40E+3nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076137((S)-2-({3-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50: 6.10E+3nMAssay Description:In vitro inhibition of [3H]GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076131((S)-2-{4-[(1H-Imidazol-2-ylmethyl)-amino]-2-naphth...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076130((S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076144((S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076127((S)-2-{[5-(2-Imidazol-1-yl-ethoxy)-biphenyl-2-carb...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076126((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076140((S)-2-{[5-(2-Imidazol-1-yl-ethoxy)-biphenyl-2-carb...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076138((S)-2-[4-((R)-2-Amino-3-mercapto-propylamino)-2-na...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076141(2-[4-((R)-2-Amino-3-mercapto-propylamino)-2-naphth...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076139((S)-2-{4-[(1H-Imidazol-4-ylmethyl)-amino]-2-naphth...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076143((S)-2-{4-[(1H-Imidazol-2-ylmethyl)-amino]-2-naphth...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076129((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-4-yl...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076135((2S)-2-(4-((1H-imidazol-4-yl)methylamino)-2-(napht...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076145((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-4-yl...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076134((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076128((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076131((S)-2-{4-[(1H-Imidazol-2-ylmethyl)-amino]-2-naphth...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076137((S)-2-({3-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50: 4.60E+4nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076132((S)-4-Methyl-2-({4-[(pyridin-4-ylmethyl)-amino]-bi...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076145((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-4-yl...)
Affinity DataIC50: 5.80E+4nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076137((S)-2-({3-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076133((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-3',5'-d...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076132((S)-4-Methyl-2-({4-[(pyridin-4-ylmethyl)-amino]-bi...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076136((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-2-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of [3H]FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50076130((S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed