Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50008681
TargetSqualene synthase(Bovine)
Cold Spring Harbor Laboratory

Curated by ChEMBL
LigandPNGBDBM50059852(N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methy...)
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Cold Spring Harbor Laboratory

Curated by ChEMBL
LigandPNGBDBM50059852(N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methy...)
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of yeast Farnesyltransferase (expressed as a GST fusion protein in Escherichia co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Cold Spring Harbor Laboratory

Curated by ChEMBL
LigandPNGBDBM50076045((S)-2-({(3S,6R,8aR)-6-Benzyl-6-[(R)-2-(9H-fluoren-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of yeast Farnesyltransferase (expressed as a GST fusion protein in Escherichia co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Cold Spring Harbor Laboratory

Curated by ChEMBL
LigandPNGBDBM50076042((S)-2-({(3S,6S,9aS)-6-[(S)-2-(9H-Fluoren-9-ylmetho...)
Affinity DataIC50: 7.00E+3nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of yeast Farnesyltransferase (expressed as a GST fusion protein in Escherichia co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Bovine)
Cold Spring Harbor Laboratory

Curated by ChEMBL
LigandPNGBDBM50076043((S)-2-{[(3S,6S,9aS)-6-((S)-2-Amino-3-mercapto-prop...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Bovine)
Cold Spring Harbor Laboratory

Curated by ChEMBL
LigandPNGBDBM50076044((S)-2-{[(3S,6R,8aR)-6-((R)-2-Amino-3-mercapto-prop...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed